2015
DOI: 10.1177/2047981614552217
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Adult onset asynchronous multifocal eosinophilic granuloma of bone: an 11-year follow-up

Abstract: Multifocal eosinophilic granuloma (EG) is a rare observation within the spectrum of histiocytosis X, generally described in children. We report the case of a 33-year-old man with multifocal EG showing an asynchronous evolution of bone lesions during a follow-up of 11 years. We also present the therapeutic approach chosen for this patient and the repeated magnetic resonance imaging (MRI) examinations used to monitor the disease with a final favorable outcome.

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“…84 The findings consist of multiple areas of bone marrow replacement. 85 As for sarcoidosis, the coexistence of active and healed lesions (partial fatty transformation) may suggest the diagnosis, which however often requires histologic confirmation. WB-MRI appears more sensitive than PET for lesion detection in pediatric forms, but PET might be superior for treatment monitoring.…”
Section: Langerhans Cell Histiocytosismentioning
confidence: 99%
“…84 The findings consist of multiple areas of bone marrow replacement. 85 As for sarcoidosis, the coexistence of active and healed lesions (partial fatty transformation) may suggest the diagnosis, which however often requires histologic confirmation. WB-MRI appears more sensitive than PET for lesion detection in pediatric forms, but PET might be superior for treatment monitoring.…”
Section: Langerhans Cell Histiocytosismentioning
confidence: 99%