Adult giant hemangioma of the larynx: A case report

Kawakami, Michiro; Hayashi, Ibuki; Yoshimura, Katsuhiro; Ichihara, Kengo; Nishikawa, Syuji; Ichihara, Takahiro

doi:10.1016/j.anl.2006.05.010

Cited by 37 publications

(31 citation statements)

References 6 publications

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“…However, only periodic observation is required because of its slow progression. Management goals include preventing or reversing functional impairment and minimizing disfigurement, pain, repeated hemorrhage, thrombocytopenia, and high output status 1, 2, 6. Adult laryngeal hemangioma is extremely rare and extensive lesions in adult laryngeal hemangioma is even less common.…”

Section: Discussionmentioning

confidence: 99%

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The impact of tumor progesterone receptor status on optimal adjuvant endocrine therapy for postmenopausal patients with early‐stage breast cancer

Punglia

Kuntz²,

Winer

et al. 2006

Cancer

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BACKGROUNDEmerging data suggest that treatment outcomes with aromatase inhibitors (AIs) and/or tamoxifen may differ for tumors that express both the estrogen receptor (ER) and the progesterone receptor (PR) (ER+/PR+) compared with those that lack PR expression (ER+/PR−). However, the optimal sequencing of AIs and tamoxifen as adjuvant therapy is not known and may differ for biologic subsets of cancers.METHODSMarkov models were used to simulate disease‐free survival (DFS) separately among postmenopausal women with ER+/PR+ cancers and women with ER+/PR− cancers. By using risk estimates reported from randomized clinical trials, treatment with 5 years of an AI alone with sequential treatment consisting of tamoxifen with crossover to an AI at 2 years was compared.RESULTSFor women with ER+/PR+ cancers, sequential therapy with tamoxifen followed by crossover to an AI at 2 years yielded modest improvements in 10‐year DFS estimates compared with planned AI monotherapy (84.3% vs. 82.2% and 68.8% vs. 64.8% for lymph node‐negative and lymph node‐positive patients, respectively). However, for women with ER+/PR− cancers, upfront treatment with an AI yielded improved outcomes with 10‐year DFS rates of 90.5% and 80.1% for the lymph node‐negative and node‐positive groups, respectively, compared with 88.2% and 76.1%, respectively, for sequential treatment with tamoxifen followed by an AI.CONCLUSIONSModeling estimates suggested that the optimal endocrine treatment strategy may differ based on the biologic features of breast cancer tumors. Patients with ER+/PR+ tumors achieved optimal 10‐year DFS estimates with tamoxifen followed by a crossover to AI therapy, whereas patients with ER+/PR− tumors fared best when they initiated treatment with AI. Cancer 2006. © 2006 American Cancer Society.

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Section: Discussionmentioning

confidence: 99%

“…Approximately 60% of all hemangiomas affect the head and neck. They frequently occur in the oral cavity and, rarely, in the larynx 2, 3. Hemangiomas of the larynx are generally classified as infantile or adult 4, 5.…”

mentioning

confidence: 99%

The impact of tumor progesterone receptor status on optimal adjuvant endocrine therapy for postmenopausal patients with early‐stage breast cancer

Punglia

Kuntz²,

Winer

et al. 2006

Cancer

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“…Magnetic resonance imaging is currently the preferred diagnostic and staging examination in this disease and demonstrates a high-intensity signal on T2-weighted sequences and an isosignal on T1-weighted sequences [4].…”

Section: Discussionmentioning

confidence: 99%

High dysphagia: A case report

Rivière

Vatin

Morvan

2015

European Annals of Otorhinolaryngology, Head and Neck Diseases

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Service d'ORL et de chirurgie cervico-faciale, hôpital d'instruction des armées Sainte-Anne, boulevard Sainte-Anne, BP 600, 83800 Toulon Naval, France DescriptionMr. M., 36 years old, with no medical history, presented to our outpatients department with pharyngeal discomfort and a foreign body sensation present for several weeks with no deterioration of his general state of health.Clinical examination revealed high dysphagia to solids and liquids with several episodes of aspiration, but no associated dysphonia or dyspnoea. Neck palpation did not reveal any abnormality.Fiberoptic nasolaryngoscopy revealed a supraglottic, submucosal, rounded mass with regular margins, arising at the expense of the left aryepiglottic fold and protruding into the ipsilateral pyriform sinus. The mucosa in contact with the mass appeared to be healthy and laryngeal mobility was preserved. (D. Rivière).Contrast-enhanced computed tomography of the neck and MRI of the pharyngolarynx were performed (Fig. 1a).Endoscopic laser resection was performed for diagnostic purposes.The operative specimen was sent for histological examination. The histological section (HES ×25) is presented in Fig. 1b. Questions• What is your radiological interpretation?• What is your differential diagnosis?• What does the histological examination reveal and what is the final diagnosis?http://dx.

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“…In adults, they are very rare and found in various laryngeal locations, i.e., epiglottis, aryepiglottic folds, arytenoids, and false or true vocal cords [21][22][23][24][25][26].…”

Section: Discussionmentioning

confidence: 99%

“…At autopsy, it was noted that the deceased was wellnourished for his age and build, with a height of 178 cm, a body weight of 80 kg and a body-mass index of 25 External examination revealed on the anterior surface of the neck a 5.5-cm long linear surgical incision directed along the neck axis and sutured with seven stitches, ascribed to tracheotomy.…”

Section: Autopsy Findingsmentioning

confidence: 99%