Adult eosinophilic gastroenteritis and hypereosinophilic syndromes

Freeman, Hugh James

doi:10.3748/wjg.14.6771

Cited by 26 publications

(24 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Eosinophilic gastroenteritis characteristically does not extend beyond the target organ [1,18] . Hence, EG lacks the multiplicity of organ involvement often found in HES and does not have the predilection to develop secondary eosinophilmediated cardiac damage [1,18] . Thus, EG can usually be distinguished from HES, although individual patients may on occasion present with overlapping features that confound classification [1,18] .…”

Section: Discussionmentioning

confidence: 99%

“…Hence, EG lacks the multiplicity of organ involvement often found in HES and does not have the predilection to develop secondary eosinophilmediated cardiac damage [1,18] . Thus, EG can usually be distinguished from HES, although individual patients may on occasion present with overlapping features that confound classification [1,18] . In our patient, multiple organ involvement was demonstrated, and there was no other possible cause of severe eosinophilia.…”

Section: Discussionmentioning

confidence: 99%

“…The diagnosis of EG is based on the following three criteria: (1) the presence of gastrointestinal symptoms, (2) biopsies showing eosinophilic infiltration of one or more areas of the GI tract, or characteristic radiologic findings with peripheral eosinophilia, and (3) no evidence of parasitic or extraintestinal disease [16] . Because EG is also of unknown etiology, the distinction from HES must be made on clinical and pathologic bases [17,18] . Eosinophilic gastroenteritis characteristically does not extend beyond the target organ [1,18] .…”

Section: Discussionmentioning

confidence: 99%

“…Because EG is also of unknown etiology, the distinction from HES must be made on clinical and pathologic bases [17,18] . Eosinophilic gastroenteritis characteristically does not extend beyond the target organ [1,18] . Hence, EG lacks the multiplicity of organ involvement often found in HES and does not have the predilection to develop secondary eosinophilmediated cardiac damage [1,18] .…”

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

A case of hypereosinophilic syndrome presenting withintractable gastric ulcers

Park¹,

Choi²,

Yang³

et al. 2009

WJG

View full text Add to dashboard Cite

We report a rare case of hypereosinophilic syndrome (HES) presenting with intractable gastric ulcers. A 71-year-old man was admitted with epigastric pain. Initial endoscopic findings revealed multiple, active gastric ulcers in the gastric antrum. He underwent Helicobacter pylori (H pylori ) eradication therapy followed by proton pump inhibitor (PPI) therapy. However, followup endoscopy at 4, 6, 10 and 14 mo revealed persistent multiple gastric ulcers without significant improvement. The proportion of his eosinophil count increased to 43% (total count: 7903/mm 3 ). Abdominal-pelvic and chest computed tomography scans showed multiple small nodules in the liver and both lungs. The endoscopic biopsy specimen taken from the gastric antrum revealed prominent eosinophilic infiltration, and the liver biopsy specimen also showed eosinophilic infiltration in the portal tract and sinusoid. A bone marrow biopsy disclosed eosinophilic hyperplasia as well as increased cellularity of 70%. The patient was finally diagnosed with HES involving the stomach, liver, lung, and bone marrow.When gastric ulcers do not improve despite H pylori eradication and prolonged PPI therapy, infiltrative gastric disorders such as HES should be considered.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

A case of hypereosinophilic syndrome presenting withintractable gastric ulcers

Park¹,

Choi²,

Yang³

et al. 2009

WJG

View full text Add to dashboard Cite

show abstract

“…The diagnosis of oeosinophilic gastroenteritis is based on the following criteria: (1) gastrointestinal symptoms, (2) oeosinophilic infiltration of one or more areas of the gastrointestinal tract and (3) exclusion of other causes for intestinal oeosinophilia (eg, drug reactions, parasitic infections, inflammatory bowel diseases, connective tissue diseases, lymphoproliferative malignancies) 12 13…”

Section: Introductionmentioning

confidence: 99%

A patient with oeosinophilic gastroenteritis and severe malnutrition improved with home parenteral nutrition

Santarpia

Cuomo²,

Camera³

et al. 2010

Case Reports

View full text Add to dashboard Cite

Oeosinophilic gastroenteritis is a chronic and rare disorder characterised by massive oeosinophilic tissue infiltration involving one or more segments of the digestive tract. The management of patients with oeosinophilic gastroenteritis is complex and the therapeutic response often poor. Here we discuss the clinical case and management of a 23-year-old man with oeosinophilic gastroenteritis since the first year of life and the decision to prescribe lifelong total parenteral nutrition.

show abstract