Adult colloid milium: a case report and literature review

Mehregan, Darius; Hooten, Joanna

doi:10.1111/j.1365-4632.2010.04737.x

Cited by 12 publications

(17 citation statements)

References 22 publications

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“…However, some studies have reported cases of colloid milium appearing on areas of skin that are not exposed to ultraviolet light. 1,2 Diagnosis is based on light microscopy study of a skin sample, which shows fissured eosinophilic colloid masses in the papillary dermis, with solar elastosis and a Grenz zone of elastin fibres that separates the lesion from the rest of the epidermis. 4 Some fibroblasts can be observed in cleft formations, together with some lymphocytes, mast cells and enlarged veins, with preservation of adnexa.…”

Section: Discussionmentioning

confidence: 99%

Adult colloid milium. An underdiagnosed and difficult to treat entity

Zamora

Simon

Sánchez

et al. 2016

Revista Médica del Hospital General de México

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Millium colloid is a rare cutaneous deposition disorder of unknown aetiology on lightexposed skin. It presents as flesh-coloured or yellow papules. A skin biopsy and light microscopy study is required for diagnosis, with findings of fissured eosinophilic colloid masses in the papillary dermis, with solar elastosis that is separated from the epidermis by a Grenz zone containing normal collagen. There is no single effective treatment. We present a case report of a 42-yearold man with papular lesions on the dorsum of both hands and a history of prolonged sun exposure. © 2015 Sociedad Médica del Hospital General de México. Published by Masson Doyma México S.A. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/ licenses/by-nc-nd/4.0/). PALABRAS CLAVE Millium coloide; Fotoexposicion Milium Coloide del Adulto. Una entidad subdiagnosticada y de difícil tratamientoResumen El millium coloide es una enfermedad de depósito, presente en áreas fotoexpuesta y de etiología desconocida. Clínicamente se identifica como lesiones de aspecto papular de color rosa o amarillo. Para su diagnóstico es necesario realizar una biopsia de piel para microscopía de luz, donde se observan masas eosinofílicas fisuradas en la dermis papilar en presencia de elastosis solar y una zona de Grenz de fibras elásticas que separa la lesión del resto de la epidermis. Hasta el momento no existe un tratamiento de elección. Se presenta el reporte de un caso de un paciente masculino de 42 años con lesiones de aspecto papular en dorso de manos, con el antecedente de exposición crónica a la luz solar.

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Section: Discussionmentioning

confidence: 99%

Adult colloid milium. An underdiagnosed and difficult to treat entity

Zamora

Simon

Sánchez

et al. 2016

Revista Médica del Hospital General de México

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“…21), neck, ears, and dorsal hands. 195 JCM is an exceedingly rare familial form of the disease with onset before puberty. The lesions are clinically indistinguishable from ACM but may occur in normal skin.…”

Section: Lipoid Proteinosismentioning

confidence: 99%

Cutaneous Deposits

Molina-Ruiz

Cerroni

Kutzner

et al. 2014

The American Journal of Dermatopathology

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: The cutaneous deposition disorders are a group of unrelated conditions characterized by the accumulation of either endogenous or exogenous substances within the skin. These cutaneous deposits are substances that are not normal constituents of the skin and are laid down usually in the dermis, but also in the subcutis, in a variety of different circumstances. There are 5 broad categories of cutaneous deposits. The first group includes calcium salts, bone, and cartilage. The second category includes the hyaline deposits that may be seen in the dermis in several metabolic disorders, such as amyloidosis, gout, porphyria, and lipoid proteinosis. The third category includes various pigments, heavy metals, and complex drug pigments. The fourth category, cutaneous implants, includes substances that are inserted into the skin for cosmetic purposes. The fifth category includes miscellaneous substances, such as oxalate crystals and fiberglass. In this article, the authors review the clinicopathologic characteristics of cutaneous deposition diseases, classify the different types of cutaneous deposits, and identify all the histopathologic features that may assist in diagnosing the origin of a cutaneous deposit.

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“…Dear Editor, Colloid milium is an uncommon cutaneous disease related to collagen and elastic fiber degeneration resulting in papillary dermal deposition of homogeneous eosinophilic masses which may display clefts and fissures. 1 Four different clinical subtypes are recognized, namely adult (the most common), juvenile, nodular and pigmented. 1 Sun exposure is thought to be a triggering factor, but hydroquinone (for the pigmented variant), ochronosis, petroleum and chemical fertilizers can also be involved in the pathogenesis.…”

Section: Dermoscopy In Adult Colloid Miliummentioning

confidence: 99%

“…1 Four different clinical subtypes are recognized, namely adult (the most common), juvenile, nodular and pigmented. 1 Sun exposure is thought to be a triggering factor, but hydroquinone (for the pigmented variant), ochronosis, petroleum and chemical fertilizers can also be involved in the pathogenesis. 1 Adult colloid milium (ACM) typically presents with yellow-brownish, translucent papules/plaques on sun-exposed areas, though covered areas and mucosae may be involved less commonly.…”

Section: Dermoscopy In Adult Colloid Miliummentioning

confidence: 99%

“…1 Sun exposure is thought to be a triggering factor, but hydroquinone (for the pigmented variant), ochronosis, petroleum and chemical fertilizers can also be involved in the pathogenesis. 1 Adult colloid milium (ACM) typically presents with yellow-brownish, translucent papules/plaques on sun-exposed areas, though covered areas and mucosae may be involved less commonly. 1 Clinical diagnosis of ACM is often straightforward, although it may sometimes be mistaken for similar conditions, with consequent diagnostic delays/mistreatments.…”

Section: Dermoscopy In Adult Colloid Miliummentioning

confidence: 99%

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