Adult coeliac disease and cigarette smoking.

Abstract

Background-Genetic predisposition and

Risk of malignancy in diagnosed coeliac disease: a 24‐year prospective, population‐based, cohort study

“…10,16 The reasons for this decrease could be related to the lower body weight of people with coeliac disease 17 or their lower rates of smoking. 18 In conclusion, in this large, prospective, populationbased cohort study we found no overall increase in the risk of incident malignancy in clinically diagnosed coeliac disease. Patients with coeliac disease are at greater risk of non-Hodgkin's lymphoma and small bowel lymphoma than the general population but the absolute risk (1 in 1421 person years and 1 in 5684 person years respectively) is very small.…”

The association between socioeconomic status and the symptoms at diagnosis of celiac disease: a retrospective cohort study

“…However, our work shows that patient factors are also likely to be relevant. While there are some published data evaluating socioeconomic characteristics in those diagnosed with CD in Europe [Snook et al 1996;West et al 2003;Ludvigsson 2005;Olen et al 2012], there is a paucity of such data in the US population with CD. One of the inherent difficulties in obtaining socioeconomic estimates is the lack of data available at the individual subject level.…”

“…In CD, the data are conflicting with regards to the impact of socioeconomic status on risk estimates of disease. While some small studies have shown no relationship between socioeconomics and CD diagnosis [Snook et al 1996;West et al 2003;Ludvigsson 2005], a recent population-based study from Sweden evaluated more than 29,000 patients and showed that diagnosed CD was less common in individuals with low socioeconomic position [Olen et al 2012]. The authors suggested that CD might therefore be under-recognized in this population.…”

An adult case of celiac sprue triggered after an ileal resection for perforated Meckel’s diverticulum

“…The disease can manifest itself by different clinical presentations. There are gastrointestinal symptoms, diarrhea and weight loss in the classical type, while extra intestinal findings are most common in the atypical or subclinical form [2][3][4] . Our patient could have been in the silent form of the disease that became overt after the triggering effect of surgery.…”

“…The silent group includes atypical presentations. Some initiating factors, such as gluten overload, surgery, giving up smoking, and infections can trigger the disease, which can become apparent in an abrupt manner [3,4] . Meckel's diverticulum is a common congenital anomaly of the small bowel.…”