Adult Acute Nonlymphocytic Leukemia in Saudi Arabia: Experience at King Khalid University Hospital in Riyadh

Abstract

Twenty-two adult patients with acute nonlymphocytic leukemia (ANLL) were analyzed. There were 15 males (68%) and 7 females (32%). Their median age was 42 years. Thirty-six percent had acute myelomonocytic leukemia (M4), and 46% had acute monocytic leukemia (M5), according to the French-American-British classification. Of 17 patients who received intensive combination chemotherapy, 47% achieved complete remission. Of the subgroup of 14 new and previously untreated patients, the complete remission rate was 57%. The rest of the patients died of septic complications. We report an increased ratio of M4 and M5 in ANLL in Saudi Arabia and an increased rate of severe septic and fungal complications.

PulmonaryAspergillosis Due to Aspergillus Terreus Var.Africanus in Acute Leukemia: Report of a Case and Review of the Literature

“…11 We are committed to concentrate further on these unusual pathogens as we see a relatively increased incidence of fungal pulmonary complications in our patients with acute leukemia. 17 In summary, we describe a case of opportunistic pulmonary multicavitary aspergillosis due to A. terreus var. africanus in a patient with acute lymphoblastic leukemia.…”