Adsorptive Stripping Voltammetry for Determination of Vanadium: A Review

Wlazłowska, Edyta; Grabarczyk, Malgorzata

doi:10.3390/ma16103646

Cited by 2 publications

(2 citation statements)

References 74 publications

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“…Vanadium is an essential micro‐nutrient present in plants, animals and algae which represents a class of non‐platinum‐based anticancer drugs [13], besides finding use in various industries [14]. Vanadium has been known to act as anti‐diabetic agent [15] in treating type‐2 diabetes.…”

Section: Introductionmentioning

confidence: 99%

Integrated quantum chemical calculations, predictive toxicity assessment, absorption, distribution, metabolism, excretion and toxicity profiling and molecular docking analysis to unveil the therapeutic potential of non‐oxovanadium(IV) and organotin(IV) complexes targeting breast cancer cells

Thakur,

Kumari,

Kumar

et al. 2024

Int J of Quantum Chemistry

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In this work, theoretical calculations of o‐phenylphenol‐based non‐oxovanadium(IV) and organotin(IV) complexes, previously prepared and reported by our group, have been carried out by density functional theory (DFT). Density functional theory quantum chemical computations were used to explore the structural and spectroscopic characteristics of the complexes in this study. The inhibitory nature of complexes were revealed via molecular docking research, which were performed against selected breast cancer cell proteins, 5NWH and 3HB5. The optimization and stability of complexes 1–6, were conducted using optimized DFT/B3LYP/6–311++G (d, p) level. Simulated computations of the molecular electrostatic potential surface were also performed to analyze the reactive behavior of the non‐oxovanadium(IV) and organotin(IV) complexes. The stability and molecular reactivity of the molecules were computed using the HOMO‐LUMO energies, energy gap, chemical potential (μ), electronegativity (χ), hardness (η), and softness (S) values. In silico analysis through molecular docking, ADMET properties and toxicity evaluation was used to assess its anticancer activity, drug‐likeness property and toxicity. The binding constant value, evaluated from molecular docking, was found to be very promising, −10.1 kcal mol−1 observed for vanadium complex 5 and the complexes were found to exhibit inhibition constant as low as 0.0378 μMol. Root‐mean‐square deviation (RMSD) has been carried out to validate molecular docking studies, which have been found to be below 2.0 Å for the complexes, indicating successful docking of the ligand‐protein complex by the program. The complexes, evaluated for their toxicity behavior in terms of Lethal Dose, based on Globally Harmonized System (GHS), have been found to be chemical safe falling under the category III and V and hence can find use as future metallo‐based drugs.

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Section: Introductionmentioning

confidence: 99%

Integrated quantum chemical calculations, predictive toxicity assessment, absorption, distribution, metabolism, excretion and toxicity profiling and molecular docking analysis to unveil the therapeutic potential of non‐oxovanadium(IV) and organotin(IV) complexes targeting breast cancer cells

Thakur,

Kumari,

Kumar

et al. 2024

Int J of Quantum Chemistry

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“…It enters the biosphere through natural phenomena (mechanical and chemical rock weathering, volcanism, forest fires, and aeolian processes) and human activity. The main sources of anthropogenic vanadium are ore mining and processing, fossil fuel combustion, agricultural chemicalization, and the production of glass, ceramics, pigments, rubber, redox batteries, plastics, and sulfuric acid [ 2 , 3 , 4 , 5 , 6 , 7 ]. Recently, its anthropogenic enrichment factors (AEFs) have increased: vanadium ranks first among the trace elements in the atmosphere and fourth among the trace elements in the world’s rivers [ 2 , 5 , 8 ].…”

Section: Introductionmentioning

confidence: 99%

Extractive Spectrophotometric Determination and Theoretical Investigations of Two New Vanadium(V) Complexes

Gavazov,

Racheva,

Saravanska

et al. 2023

Molecules

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Two new vanadium (V) complexes involving 6-hexyl-4-(2-thiazolylazo)resorcinol (HTAR) and tetrazolium cation were studied. The following commercially available tetrazolium salts were used as the cation source: tetrazolium red (2,3,5-triphenyltetrazol-2-ium;chloride, TTC) and neotetrazolium chloride (2-[4-[4-(3,5-diphenyltetrazol-2-ium-2-yl)phenyl]phenyl]-3,5-diphenyltetrazol-2-ium;dichloride, NTC). The cations (abbreviated as TT+ and NTC+) impart high hydrophobicity to the ternary complexes, allowing vanadium to be easily extracted and preconcentrated in one step. The complexes have different stoichiometry. The V(V)–HTAR–TTC complex dimerizes in the organic phase (chloroform) and can be represented by the formula [(TT+)[VO2(HTAR)]]2. The other complex is monomeric (NTC+)[VO2(HTAR)]. The cation has a +1 charge because one of the two chloride ions remains undissociated: NTC+ = (NT2+Cl−)+. The ground-state equilibrium geometries of the constituent cations and final complexes were optimized at the B3LYP and HF levels of theory. The dimer [(TT+)[VO2(HTAR)]]2 is more suitable for practical applications due to its better extraction characteristics and wider pH interval of formation and extraction. It was used for cheap and reliable extraction–spectrophotometric determination of V(V) traces in real samples. The absorption maximum, molar absorptivity coefficient, limit of detection, and linear working range were 549 nm, 5.2 × 104 L mol−1 cm−1, 4.6 ng mL−1, and 0.015–2.0 μg mL−1, respectively.

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Adsorptive Stripping Voltammetry for Determination of Vanadium: A Review

Cited by 2 publications

References 74 publications

Integrated quantum chemical calculations, predictive toxicity assessment, absorption, distribution, metabolism, excretion and toxicity profiling and molecular docking analysis to unveil the therapeutic potential of non‐oxovanadium(IV) and organotin(IV) complexes targeting breast cancer cells

Integrated quantum chemical calculations, predictive toxicity assessment, absorption, distribution, metabolism, excretion and toxicity profiling and molecular docking analysis to unveil the therapeutic potential of non‐oxovanadium(IV) and organotin(IV) complexes targeting breast cancer cells

Extractive Spectrophotometric Determination and Theoretical Investigations of Two New Vanadium(V) Complexes

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