Adsorption, Protein, Batch

Adams, William R.; Goetz, V; Lee, Ann L.

doi:10.1002/0471250589.ebt004

Cited by 1 publication

(2 citation statements)

References 32 publications

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“…We will have much to say about this in our discussion of design strategy. As this review is being written, fixed-bed sorption operations, in particular various forms of chromatography (Adams et al, 1999;Cramer and Natarajan, 1999;Guiochon et al, 1994;Kaarsnaes, 1999;Lightfoot, 1999;McGuire and Bothwell, 1999;Rathore and Velayudhan, 2003;Roth and Yarmush, 1999;Thoemmes, 1999) are dominant for recovery of valuable products from impure dilute solutions and for separations of closely related materials. They will be discussed in some detail below.…”

Section: Final Purificationmentioning

confidence: 99%

“…A great variety of sorbents is now available (Adams et al, 1999), and chief among them for preparative purposes are size exclusion (SEC; Roth and Yarmush, 1999), ionexchange (IX; Cramer and Natarajan, 1999), hydrophobic interaction (HIC; Kaarsnaes, 1999), and ''affinity'' (Stahl et al, 1999) adsorbents. There are a great many subtypes within each group, including for example, both weak and strong acid and base exchangers -and many gradations of affinity systems.…”

Section: Practical Considerationsmentioning

confidence: 99%

See 1 more Smart Citation

Bioseparations

Lightfoot

Moscariello

2004

Biotech & Bioengineering

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Here we review key applications of separation technology in applied biology. We first sketch out the field as a whole, but then narrow our scope to the processing of fermentation products, particularly to high-value biologicals such as proteins and nucleotides. We go on to provide a qualitative overview describing the importance and general nature of this large field, major trends, and the strategies that have proven most fruitful in evolving effective separation and purification processes. We then give a detailed description of individual separations equipment and the principles governing their operation. We concentrate throughout on making the available literature accessible to the reader; we provide what is hoped to be a representative set of basic references. However, these references, in turn, include some that suggest promising new developments as well as a number of more specialized reviews. We hope that our overall result provides the reader with access to the most relevant literature. B

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