Adsorption of rosmarinic acid from aqueous solution on chitosan powder

Accumulation of 2-Acetylamino-5-mercapto-1,3,4-thiadiazole in chitosan coatings for improved anticorrosive effect on zinc

“…An alternative approach can be to take advantage of the gel-form matrix and the positive charge of the protonated chitosan chains (Figure 1 A and Figure 1s Bsupplementary data), which make the material an efficient adsorbent for negatively charged molecules [12,13,14]. A further advantage of chitosan-coating is the transparency of the layers, providing protection without modifying the visual aspect of the coated object [15].…”

Rosmarinic Acid and Ulvan from Terrestrial and Marine Sources in Anti-Microbial Bionanosystems and Biomaterials

“…Madureira et al [99] later demonstrated that RA-loaded nanoparticles with zeta potential of 20-30 mV are suitable to adhere to the intestinal epithelium, releasing the antimicrobial compound to the gut and preventing or controlling intestinal disorders provoked by bacterial food pathogens (i.e., Bacillus cereus, Escherichia coli O157, Listeria innocua, Staphylococcus aureus, Salmonella typhimurium, and Yersinia enterocolitica). As an alternative to encapsulation in spherical CS particles, adsorption of RA on CS powder was also studied, obtaining waterinsoluble RA-CS complexes characterized by a high amount of immobilized RA [100,101]. From kinetic studies it was established that the adsorption of RA on CS powder occurred in two steps: in the first step RA molecules were attached to the ionized amine groups on the surface of the CS powder due to electrostatic interaction, while in the next step the previously adsorbed RA molecules became the sites for adsorption of additional RA molecules due to hydrophobic interaction.…”

Construction of a layer-by-layer self-assembled rosemarinic acid delivery system on the surface of CFRPEEK implants for enhanced anti-inflammatory and osseointegration activities

“…As for the LBL process, the load of RA should be given priority in the selection of biobased polyelectrolyte pairs. Recently reported local RA delivery systems include chitosan complexes, 29,30 magnetite microspheres, 31 liposome vesicles, 32 electric spray particles, 33 polyelectrolyte microgels, 34 cyclodextrin complexes, 35 etc. Among all, the simplest system of chitosan and rosmarinic acid complex (CS@RA) has attracted extensive attention, and chitosan has been confirmed to load RA through ion interactions between amino and carboxyl groups as well as hydrophobic interactions between helical domains and hydrocarbon chains.…”