Adsorption of phenylalanine onto polymeric resins: equilibrium, kinetics and operation of a parametric pumping unit

Abstract

Adsorption of D, L-Phenylalanine onto polymeric adsorbents (Amberlite XAD-4 and XAD-16; Sephabeads SP206 and SP207) was studied. Adsorption equilibrium isotherms were measured by batch equilibration at 15 and 40°C showing the possibility of using a parametric pumping technique for aminoacid purification/recovery. Dynamic studies in a laboratory adsorption column Amicon Column (22 x 500 mm) were carried out to further screen adsorbents and obtain mass transfer parameters to be used in the modeling, simulation and operation of the pilot parametric pumping unit. The pilot plant includes a Amicon Columnn (90 x 1000 mm) and is completely automated. A package for the simulation of this cyclic operation was developed. Simulated and experimental results using Sephabeads SP206 (Mitsubishi Kasei Corporation, Japan) are in good agreement. 0 1998 Elsevier Science B.V.

Comparative study of the adsorption of phenol and salicylic acid from aqueous solution onto nonionic polymeric resins

“…Nonionic polymeric resins have been previously successfully used for phenol and phenolic derivatives adsorption [19][20][21][22]. Table 1 summarizes the data supplied by the manufacturers on the physical characteristics of the resins used in this work.…”

Removal of phenylalanine from aqueous solutions with thermo-chemically modified corn cobs as adsorbents

“…Adsorption is also the process employed for the removal of phenylalanine from protein hydrolysates in the preparation of Phe-free dietary formulas for treatment of phenylketonuria patients (Clark, Alves, Franca, & Oliveira, 2012). Many studies have been reported in the scientific literature dealing with the adsorption of phenylalanine on materials such as activated carbons, zeolites, ion exchangers, polymeric resins and others (Díez, Leitão, Ferreira, & Rodrigues, 1998;Titus, Kalkar, & Gaikar, 2003;Garnier et al, 2007;Piao, Liu, Li, & Wang, 2009;Ghosh, Badruddoza, Uddin, & Hidajat, 2011;Fei-Peng, Zhao-Di, Li, & XiaoQing, 2012). However, high costs are associated with the production and regeneration of such adsorbents and these costs could be reduced by the use of low-cost adsorbents (Clark et al, 2012).…”

Evaluation of the performance of an agricultural residue-based activated carbon aiming at removal of phenylalanine from aqueous solutions

“…An alternative to reduce costs is the use of residues from the food industry in the development of protein hydrolysates. However, the PHE contents in the produced hydrolysate must be reduced to acceptable levels, usually by adsorption (Díez, Leitão, Ferreira, & Rodrigues, 1998;Long et al, 2009;Titus, Kalkar, & Gaikar, 2003). Thus, high costs are still associated with the PHE removal step given the use of synthetic adsorption materials, and such costs could be reduced by the use of residue-based adsorbents .…”