Adsorption of Orotic Acid on Ag Colloidal Nanoparticles

Andronie, Luisa; Mireşan, Vioara; Pop, Ioana; Răducu, Camelia; Coroian, Aurelia; Coroian, C.; Cocan, Daniel; Constantinescu, Radu

doi:10.15835/buasvmcn-asb:10794

Cited by 4 publications

(6 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…41,19 Furthermore, the use of routine stained tissue sections or cells for RS analysis has been limited due to background signals that interfere with the Raman spectra. 42 Therefore, to prevent the loss of critical cellular information, RS should be compatible, as much as possible, with conventional sample preparation, without the need for further processing. This challenge might be overcome by resolving noninherent signals from current cytological preparations from the cell spectra.…”

Section: ■ Results and Discussionmentioning

confidence: 99%

“…For instance, a study compared Raman signals of unprocessed tissue preparations and dewaxed tissue sections, demonstrating that tissue processing has a significant impact on the extracellular structure, in particular on the lipidic structure . Also, in the clinical applications of RS related with endoscopy, background signals due to the use of fiber optics have been reported as one of the main issues. , Furthermore, the use of routine stained tissue sections or cells for RS analysis has been limited due to background signals that interfere with the Raman spectra . Therefore, to prevent the loss of critical cellular information, RS should be compatible, as much as possible, with conventional sample preparation, without the need for further processing.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Unravelling the Metabolic Progression of Breast Cancer Cells to Bone Metastasis by Coupling Raman Spectroscopy and a Novel Use of Mcr-Als Algorithm

et al. 2018

View full text Add to dashboard Cite

Raman spectroscopy (RS) has shown promise as a tool to reveal biochemical changes that occur in cancer processes at the cellular level. However, when analyzing clinical samples, RS requires improvements to be able to resolve biological components from the spectra. We compared the strengths of Multivariate Curve Resolution (MCR) versus Principal Component Analysis (PCA) to deconvolve meaningful biological components formed by distinct mixtures of biological molecules from a set of mixed spectra. We exploited the flexibility of the MCR algorithm to easily accommodate different initial estimates and constraints. We demonstrate the ability of MCR to resolve undesired background signals from the RS that can be subtracted to obtain clearer cancer cell spectra. We used two triple negative breast cancer cell lines, MDA-MB 231 and MDA-MB 435, to illustrate the insights obtained by RS that infer the metabolic changes required for metastasis progression. Our results show that increased levels of amino acids and lower levels of mitochondrial signals are attributes of bone metastatic cells, whereas lung metastasis tropism is characterized by high lipid and mitochondria levels. Therefore, we propose a method based on the MCR algorithm to achieve unique biochemical insights into the molecular progression of cancer cells using RS.

show abstract

Section: ■ Results and Discussionmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Unravelling the Metabolic Progression of Breast Cancer Cells to Bone Metastasis by Coupling Raman Spectroscopy and a Novel Use of Mcr-Als Algorithm

et al. 2018

View full text Add to dashboard Cite

show abstract

“…Naphthols have recently attracted much interest due to their large nonlinear optical properties (NLOP). This fact raised technological importance in various photonic technologies such as optical switching, optical communications, computing, wave guiding, compact 3D data storage and micro fabrication, chemical and biological sensing, optical power limiting, bioimaging, signal and data processing, and many other current items in materials science [6].…”

Section: Introductionmentioning

confidence: 99%

Analysis of the Molecular Structure of N'-((2-hydroxynaphthalen-1-yl)methylene)isobutyrohydrazide

Ataol

2022

Erzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi

View full text Add to dashboard Cite

Bu çalışmada kapalı formülü C15H16N2O2 olan N'-((2-hidroksinaftalin-1-yl)metilen)izobütirohidrazid bileşiğinin moleküler yapısı Yoğunluk Fonksiyonel Teorisi (YFT) hibrid baz fonksiyonlarından B3LYP ve 6-311+G(d, p) baz seti kullanılarak araştırılmıştır. C15H16N2O2 bileşiğinin moleküler yapısı, ilk olarak gaz, kloroform, etanol ve su ortamlarında optimize edilmiştir. Daha sonra optimize edilen moleküler yapılar kullanılarak moleküler elektrostatik potansiyel (MEP) haritası elde edilmiş, farklı çözücü ortamlarında moleküler orbital enerji seviyeleri ve enerji değerleri araştırılmıştır. Farklı ortamlar için elde edilen moleküler orbital enerji değerlerinden kimyasal reaktivite parametreleri türetilmiştir. Zamana Bağlı Yoğunluk Fonksiyonel Teorisi (ZB-YFT) kullanılarak farklı ortamlar için bileşiğin uyarılmış durumda UV spektraları hesaplatılmış ve moleküler orbitallere atomik orbitallerden yüzde katkılar hesaplatılmıştır. Son olarak, moleküler yapının (ΔN) yük transfer ve (ΔE) enerji düşürme değerleri kullanılarak Sn, Hg, Cd ve Zn gibi bazı ağır metaller ile C15H16N2O2 bileşiği arasındaki etkileşim araştırılmıştır.

show abstract

“…This differentiates the 1-naphthyl substitution from the 2-naphthyl substitution, as shown in Figure 4 b [ 58 ]. The weak peak at 1556 cm −1 and moderate peak at 1462 cm −1 represent the C-C stretching and C-H in-plane bending modes, respectively [ 59 ]. The peak at 1238 cm −1 represents the ring C-C and C-O stretching modes.…”

Section: Resultsmentioning

confidence: 99%

Cellulose Functionalization Using N-Heterocyclic-Based Leaving Group Chemistry

Negi,

Tehrani-Bagha

2024

Polymers

View full text Add to dashboard Cite

There has been continuous interest in developing novel activators that facilitate the functionalization of cellulosic materials. In this paper, we developed a strategy in which trisubstituted triazinium salts act as cellulose preactivators. As leaving groups, these triazinium salts utilize N-heterocycles (pyridine, imidazole, and nicotinic acid). Initially, we optimized the synthetic route for developing these novel cellulose preactivators (triazinium salts), whose structures were confirmed using NMR spectroscopy. The surface zeta potential of cellulose changed from a negative value to a positive one after preactivation due to the cationic nature of these preactivators. To enhance the scope of the study, we functionalized the cellulose-preactivated materials with a series of amine- or hydroxy-containing aliphatic and aromatic hydrocarbons, nucleophilic amino acids (cysteine), colorants (2-aminoanthraquinone and 2-amino-3-methyl-anthraquinone), and biopolymer (zein protein). The treated samples were analyzed using FTIR, time-gated Raman spectroscopy, and reflection spectroscopy, and the success of the functionalization process was validated. To widen the scope of such chemistries, we synthesized four reactive agents containing N-heterocyclic-based leaving groups (pyridine and nicotinic acid) and successfully functionalized cellulose with them in one step. The proposed single- and two-step functionalization approaches will provide opportunities for chemically linking various chemical compounds to cellulose for different applications.

show abstract

Adsorption of Orotic Acid on Ag Colloidal Nanoparticles

Cited by 4 publications

References 5 publications

Unravelling the Metabolic Progression of Breast Cancer Cells to Bone Metastasis by Coupling Raman Spectroscopy and a Novel Use of Mcr-Als Algorithm

Unravelling the Metabolic Progression of Breast Cancer Cells to Bone Metastasis by Coupling Raman Spectroscopy and a Novel Use of Mcr-Als Algorithm

Analysis of the Molecular Structure of N'-((2-hydroxynaphthalen-1-yl)methylene)isobutyrohydrazide

Cellulose Functionalization Using N-Heterocyclic-Based Leaving Group Chemistry

Contact Info

Product

Resources

About