Adsorption of Organic Compounds by Commercial Filter Papers and its Implication on Quantitative-Qualitative Chemical Analysis

Chiou, Win L.; Smith, Lloyd D.

doi:10.1002/jps.2600590627

Cited by 17 publications

(2 citation statements)

References 21 publications

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“…Curcumin (50 mg) was added to 50 ml of water in an iodine flask and kept in temperature controlled magnetic stirrer maintained at 37° for 24 h. After shaking, the flasks were kept in incubator at 37±0.5° for equilibration for 12 h. Then the solution was filtered by whatman filter paper and the clear filtrate was assayed spectrophotometrically at 430 nm against blank solution. Form the available literature[5] the adsorption to Filter II (Whatman Filter) was much lower and in most cases negligible.…”

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confidence: 99%

Role of surfactant and pH in dissolution of curcumin

Rahman¹,

Telny

Ravi

et al. 2009

Indian J Pharm Sci

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Curcumin is a phytoconstituent with wide range of biological activity. It is poorly soluble in water. In the present study a new dissolution medium was developed, as there is no validated dissolution method available in the literature. The composition of the dissolution medium was selected on the basis of solubility data at 37°. Solubility data revealed that addition of surfactant may be suitable as a dissolution medium. The suitability of dissolution medium (0.5% sodium lauryl sulphate in water) relative to the other dissolution medium was evaluated. The selected dissolution media was used for the evaluation of curcumin tablets.

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confidence: 99%

Role of surfactant and pH in dissolution of curcumin

Rahman¹,

Telny

Ravi

et al. 2009

Indian J Pharm Sci

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“…This may explain why the study of Kuhn et al 23 detected no adherence to the feeding tube, because that study was conducted at a pH of 8. Warfarin also binds to filters, up to 100%, as documented here and elsewhere 24 . Various plastics will yield varying results.…”

Section: Discussionmentioning

confidence: 60%

Warfarin Bioavailability With Feeding Tubes and Enteral Formula

Klang

Graham

McLymont

2010

J Parenter Enteral Nutr

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Experimental gouty synovitis caused by bacterial endotoxin adsorbed onto urate crystals

Arman

Carlson

Kling

et al. 1974

Arthritis & Rheumatism

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We used a laboratory model of gouty synovitis giving quantitative dosedependent results with urate injection intrasynovially into the knee joint of dogs. We found that when precautions were taken to prevent any possible endotoxin contamination of the urate crystals, they became significantly less active. Endotoxin by itself, from Escherichia coli, was very potent in causing pain and leukocytic infiltration into the knee joint. Such endotoxin was readily and firmly adsorbed onto urate crystals. A small dose of urate crystals that caused no pain by itself became very painful when the crystals were allowed to adsorb endotoxin in vitro. When this same small non-painful dose of urate crystals was given into the joint, and the dog also received endotoxin by the oral route, signs of pain arose very clearly. It is known that gouty patients even when in remission may have crystals of sodium urate in the synovial fluid. It would therefore appear possible that if such urate crystals were to adsorb an endotoxin passing from the gastrointestinal tract into the plasma, thence into the synovial space, the patients may develop an attack of gout.Why do acute attacks of gout occur so sporadically in patients who have persistent hyperuricemia? This question was asked by the late Dr. Gutman in a recent review on gout (1). Crystals of sodium urate are consistently demonstrable between attacks in joint aspirates of spontaneously occurring acute gouty arthritis, as shown by McCarty and Hollander (2), and yet such attacks are only sporadic. There must therefore be factors other than urate crystals essential to triggering the acute attack. Talbott states (3) that acute infections are frequent associates of gout, and that an acute pharyngitis may be complicated a few days later by acute articular distress.

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Adsorption of Organic Compounds by Commercial Filter Papers and its Implication on Quantitative-Qualitative Chemical Analysis

Cited by 17 publications

References 21 publications

Role of surfactant and pH in dissolution of curcumin

Role of surfactant and pH in dissolution of curcumin

Warfarin Bioavailability With Feeding Tubes and Enteral Formula

Experimental gouty synovitis caused by bacterial endotoxin adsorbed onto urate crystals

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