Adsorption of Azorubine E122 dye via Na-mordenite with tryptophan composite: batch adsorption, Box–Behnken design optimisation and antibacterial activity

This study looked at the doxorubicin hydrochloride (DOX) anticancer drug's adsorption characteristics on a silverbased metal−organic framework (Ag-MOF). X-ray diffraction (XRD), scanning electron microscopy (SEM), and X-ray photoelectron spectroscopy (XPS) were used for the characterization of Ag-MOF. The pore volume and surface area of Ag-MOF were determined through Brunauer−Emmett−Teller (BET) testing at 77 K to be 0.509 cm 3 /g and 676.059 m 2 /g, respectively. Adsorption at pH 6 was established to be the best for DOX compared to alkaline solution. Ag-MOF has a good capacity for eliminating DOX (1.85 mmol/g), according to adsorption experiments. From the adsorption results, we can find that Langmuir is the most fitted adsorption isotherm model and the pseudo-second order model best fitted the adsorption kinetics. The energy of activation for adsorption, which was determined to be 15.23 kJ/mol, also supported a chemisorption process. The mechanism of adsorption was evaluated, and details of all possible interactions between DOX and Ag-MOF were illustrated. On the other hand, while examining the impact of temperature, we identified the thermodynamic constraints as ΔG°, ΔH°, and ΔS°and confirmed that the reaction was an endothermic one and spontaneous. Even after numerous reuse cycles, the efficiency remained constant. The synthetic adsorbent was remarkably recyclable at a rate of more than 91.6%. By using the MTT assay, the cytotoxicity of the tested Ag-MOF and DOX@Ag-MOF against human breast cancer cells (MCF-7) was evaluated in vitro. The in vitro antimicrobial activity of Ag-MOF and DOX@Ag-MOF was also tested.

Section: Resultsmentioning

confidence: 99%

Section: Resources and Techniquesmentioning

confidence: 99%

Application of Metal–Organic Frameworks for Efficient Removal of Doxorubicin Hydrochloride: Removal Process Optimization and Biological Activity

Alkhamis,

Aljohani,

Ibarhiam

et al. 2023

“…Sufficient active sites for adsorbate removal depend on the adsorbent dosage, making it a basis factor in the adsorption process . At 293 K, the effect of the MIL-88(Fe)-NH 2 adsorbent dose on the adsorption of 50 mg L –1 of 2,4-D was studied using 0.02 to 0.25 g of the adsorbent dosages.…”

Section: Resultsmentioning

confidence: 99%

Efficient Adsorption and Removal of the Herbicide 2,4-Dichlorophenylacetic Acid from Aqueous Solutions Using MIL-88(Fe)-NH₂

Alluhaybi,

Alharbi,

Alshammari

et al. 2023

Metal−organic frameworks (MOFs), a material known for its multifunctionality, chemical stability, and high surface area, are now commonly utilized as an adsorbent for water treatment. The MOF (MIL-88(Fe)-NH 2 ) was synthesized and used to remove the commonly used toxic herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) from water. The MIL-88(Fe)-NH 2 MOF was fully characterized using multiple techniques. A systematic investigation was conducted to evaluate the key parameters that impact the adsorption process, which include coexisting anions, adsorbent dosage, and solution pH. The adsorption isotherm was fitted using the Langmuir model, while the kinetics were fitted using pseudo-second-order. The adsorption process was both chemisorption and endothermic. The capacity for adsorption increased with rising temperatures. The MIL-88(Fe)-NH 2 adsorbent has a maximum adsorption capacity of 345.25 mg g −1 for removing 2,4-D, significantly higher than previous adsorbents used for this purpose. The adsorption mechanism could be ascribed to hydrogen bonding, pore filling, π−π conjugations between the 2,4-D molecules and the MIL-88(Fe)-NH 2 adsorbent, and electrostatic interactions. Furthermore, the adsorption capacity of MIL-88(Fe)-NH 2 adsorbent showed only a slight decrease after five successive recycles, and it could be easily regenerated through solvent washing. When used in environmental water samples, especially those containing electronic wastes, the MIL-88(Fe)-NH 2 adsorbent demonstrated satisfactory adsorption capacity and reusability. The MIL-88(Fe)-NH 2 adsorbent is more practical and reusable and has better adsorption capacity and shorter equilibrium time compared to previously reported adsorbents.

“…The La 3d core level spectrum shows seven peaks, all of which result from the spin–orbital splitting of the La 3d 5/2 and 3d 3/2 states (III). Figure e signifies the analysis of the XPS image of La-MOF …”

Section: Resultsmentioning

confidence: 99%

Efficient Removal of Deltamethrin from Aqueous Solutions Using a Novel Lanthanum Metal–Organic Framework: Adsorption Models and Optimization via Box–Behnken Design

Alkhatib,

Ibarhiam,

Alrefaei

et al. 2023

Self Cite

Eliminating pesticides is essential for lowering the dangers to our environment. To do this effectively, it is crucial to find adsorbents with remarkable adsorption capacities, easy retrieval, and separation. Metal−organic frameworks (MOFs) have been extensively recognized for their exceptional ability to absorb pollutants. Therefore, we used novel lanthanum metal− organic frameworks (La-MOFs) to eliminate deltamethrin (DEL) from aqueous solutions. We proved through experimentation that the La-MOF is an efficient adsorbent for DEL from water. A study of the material revealed that the adsorbent had a surface area of 952.96 m 2 per gram and a pore volume of 1.038 cm 3 /g. These outcomes show how this substance can absorb particles. Utilizing kinetic models and conforming to the pseudo-second-order model, a thorough analysis of the efficiency of DEL adsorption onto La-MOF was conducted. To create a perfectly tailored approach, we utilized many parameters. The synthetic La-MOF adsorbent may undergo up to five steps of adsorption−desorption and has exceptional cyclability and reusability. To confirm purifying wastewater samples in the laboratory, the presentation of the established adsorbent was evaluated. For the management of industrial effluent and water filtration, the La-MOF adsorbent offered a simple and effective solution. Our investigation suggests that the method we describe for removing DEL from wastewater samples using the La-MOF adsorbent is unique.