Adsorption isotherm model for multicomponent adsorbate—adsorbate interactions

Moreau, M.; Valentin, Patrick; Vidal-Madjar, Claire; Lin, Bing Chang; Guiochon, Georges

doi:10.1016/0021-9797(91)90308-u

Cited by 67 publications

(49 citation statements)

References 8 publications

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“…[53][54][55] BSA is well known to multilayer in static systems. 56,57 The most common model used to describe adsorbate-adsorbate interactions, following the initial establishment of a monolayer, is the Moreau isotherm, 42,58 presented as:…”

mentioning

confidence: 99%

Roles of interstitial fraction and load conditions on the dynamic binding capacity of proteins on capillary‐channeled polymer fiber columns

Wang

Marcus

2014

Biotechnology Progress

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Capillary-channeled polymer (C-CP) fibers are used as a stationary phase for ion-exchange chromatography of proteins. Collinear packing of the fibers permits operation at high linear velocities (Uo > 100 mm s(-1)) and low backpressure (<2,000 psi) on analytical-scale columns. Rapid solvent transport is matched with very efficient solute mass transfer as fibers are virtually non-porous with respect to the size of the target protein molecules. Lack of porosity of course limits the equilibrium binding capacity of stationary phases. Breakthrough curves and frontal analysis are used to better understand trade-offs between the kinetic and thermodynamic properties as C-CP fibers are applied in preparative situations. Fiber columns packed to different interstitial fraction values affect both the total fiber surface area (e.g., equilibrium binding capacity [EBC]) and the permittivity to flow and mass transport characteristics (e.g., dynamic binding capacity [DBC]). The EBC of the nylon 6 C-CP fibers was found to be 1.30 mg g(-1), with isotherms that were best matched by a Moreau model, showing linearity up to solute concentrations of ∼0.4 mg mL(-1). Isotherms generated under flow conditions were equally well approximated using Langmuir, Freundlich, and Moreau isotherm models. Fairly linear responses were seen up to the maximum load concentration of 1.2 mg mL(-1). Counterintuitively, dynamic studies revealed that conditions of high column porosity yielded a DBC that is ∼70% higher than the EBC. These findings point to potential advantages in terms downstream processing applications, where protein throughput and yield are critical metrics.

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confidence: 99%

Roles of interstitial fraction and load conditions on the dynamic binding capacity of proteins on capillary‐channeled polymer fiber columns

Wang

Marcus

2014

Biotechnology Progress

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“…Importance of different interactions was elucidated by correlating the adsorption data using the Moreau equation (Eq. 2) that has been derived for systems including both adsorbent-adsorbate and adsorbate-adsorbate interactions (Moreau et al 1991). The calculated isotherms are shown in Fig.…”

Section: Adsorption Of Pure Phospholipids From Rapeseed Oilmentioning

confidence: 99%

“…The data were correlated with the Moreau isotherm equation (Moreau et al 1991;Gritti and Guiochon 2004) given in Eq. (2) for single-component adsorption.…”

Section: Adsorption Measurementsmentioning

confidence: 99%

Phospholipid adsorption from vegetable oils on acid-activated sepiolite

et al. 2015

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In this study, adsorption of natural and model phospholipids (PL) from camelina and rapeseed oils on acid-activated sepiolite has been studied. Adsorption isotherms were determined for total phosphorus and for individual PL at different conditions. Influence of aciddegumming with citric acid as well as of type and ionic form of the phospholipid was investigated. The experimental data were correlated using the Moreau isotherm. The results show that neutral PLs, such as phosphatidylcholines, adsorb as ordered monolayers with molecular area of 1.3 nm 2 /molecule. Phosphatidic acids have similar adsorption capacity when in free acid form but the interaction with the clay surface is much weaker. Sodium salt gives substantially lower saturation capacity because of electrostatic repulsion between the adsorbed PL molecules and between PL and the clay surface. Calcium and magnesium salts have very low capacity and seem to be incapable to form any ordered structures on the clay surface.

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“…In this work, three different models were used to fit single-component adsorption isotherms of paracetamol on AC. They can be classified into: isotherm models for homogeneous surfaces without lateral interactions such as Langmuir equation [63]; isotherm models for homogeneous surfaces with lateral interactions such as Moreau n = 3 equation [64] and isotherm models for heterogeneous surfaces without lateral interactions such as Jovanovic-Freundlich equation [65].…”

Section: Adsorption Modelingmentioning

confidence: 99%

Interaction of paracetamol and 125I-paracetamol with surface groups of activated carbon: theoretical and experimental study

Hernández-Valdés

Enríquez-Victorero

Pizarro-Lou³

et al. 2015

J Radioanal Nucl Chem

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The selection of activated carbon (AC) filters for water decontamination is currently carried out empirically. The low concentrations of drugs in the environment make the radioisotope labeling a valuable tool for physical and chemical studies of the adsorption process. A theoretical study of paracetamol and 125 I-paracetamol adsorption onto AC was performed to evaluate the interactions between pollutants and surface groups (SG) of AC. Paracetamol was labeled with 125 I and adsorption isotherms were obtained using radioanalytical and spectrophotometric techniques. The radioanalytical method overestimates the paracetamol adsorption. The validity of the chosen approach for qualitative assessment of SG influence over the adsorption process was demonstrated.

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Adsorption isotherm model for multicomponent adsorbate—adsorbate interactions

Cited by 67 publications

References 8 publications

Roles of interstitial fraction and load conditions on the dynamic binding capacity of proteins on capillary‐channeled polymer fiber columns

Roles of interstitial fraction and load conditions on the dynamic binding capacity of proteins on capillary‐channeled polymer fiber columns

Phospholipid adsorption from vegetable oils on acid-activated sepiolite

Interaction of paracetamol and 125I-paracetamol with surface groups of activated carbon: theoretical and experimental study

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