Adrenocortical oncocytoma in a child

Gumy‐Pause, Fabienne; Bongiovanni, Massimo; Wildhaber, Barbara E.; Jenkins, Jesse J.; Chardot, Christophe; Özşahin, Hülya

doi:10.1002/pbc.21090

Cited by 33 publications

(24 citation statements)

References 17 publications

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“…An adrenocortical oncocytic neoplasm occurring with an aldosteronoma has been described [57,58] as well as very rare cases of virilizing adrenocortical oncocytic neoplasm in a female child [59][60][61] or old woman [62] , an adrenocortical oncocytic carcinoma producing testosterone [63] or presenting with pseudoprecocious puberty induced by adrenocortical oncocytoma [64] and an adrenal oncocytic neoplasm producing cortisol and testosterone [65] or cortisol and aldosterone [66] . A case of an adrenocortical oncocytic neoplasm producing interleukin (IL)-6 has been reported [67] .…”

Section: Diagnosismentioning

confidence: 99%

Adrenal Oncocytic Neoplasm: A Systematic Review

Mearini¹,

Sordo

Costantini³

et al. 2012

Urol Int

151

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Introduction: Oncocytic neoplasms as tumors arising in the adrenal glands are rare, usually considered as nonfunctional and benign. In the current literature, there are extremely limited reports of adrenal oncocytic neoplasms; as to date, only 147 cases have been described. The rarity of the event prompted this study which reviews and presents the incidence, histology, diagnosis and therapy of adrenal oncocytic neoplasms. Materials and Methods: A review by systematic literature search was done using the MEDLINE®/Cochrane libraries from 1950 to date using the medical subject headings ‘oncocytoma', ‘adrenal gland', ‘adrenal oncocytoma', ‘adrenal oncocytic neoplasm' and ‘adrenal oncocytic carcinoma'. Results: Adrenal oncocytic neoplasm is a rare disease, usually incidentally detected because only 17% are functional adrenal masses. The typical oncocyte displays abundant granular eosinophilic cytoplasm, due to the accumulation of mitochondria. Computed tomography and magnetic resonance imaging are not able to identify or differentiate benign and malignant oncocytic neoplasms. The mainstay of therapy is adrenalectomy, recently performed by laparoscopy. The prognosis is good for benign tumors, while adrenocortical oncocytic carcinoma has a poor survival rate of only 5 years. Conclusions: Adrenal oncocytic neoplasm, a rare and mostly benign tumor, usually presents as an incidental, large adrenal mass; surgery is the mainstay of therapy, by means of laparoscopy which is now the most diffuse approach to adrenalectomy.

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Section: Diagnosismentioning

confidence: 99%

Adrenal Oncocytic Neoplasm: A Systematic Review

Mearini¹,

Sordo

Costantini³

et al. 2012

Urol Int

151

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“…Gumy-Pause et al reported the first pediatric oncocytoma in a 12-year-old girl who presented with fatigue, headaches, abdominal pain, acne vulgaris, and elevated androstenedione and total testosterone levels [3]. These authors performed left adrenalectomy for the patient and reported complete excision as the most important criterion for prognosis.…”

Section: Discussionmentioning

confidence: 95%

The first laparoscopic resection of an aldosterone-secreting adrenocortical oncocytoma in a child

Akın

Erginel

Tanık

et al. 2014

Journal of Pediatric Surgery Case Reports

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a b s t r a c tOncocytomas of the adrenal cortex are usually benign and nonfunctional, consisting of oncocytes in which the cytoplasm becomes eosinophilic due to the accumulation of abnormal mitochondria. Oncocytomas can exist in many organs and are frequently found in the salivary gland, kidneys, thyroid gland, parathyroid gland, and hypophysis. Functioning oncocytomas are very rarely observed in children, and no more than ten cases have been reported in the literature. Here, we present the first report of laparoscopic excision of an aldosterone-secreting adrenocortical oncocytoma in a child.

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“…Depuis, une cinquantaine de cas ont été signalés de façon sporadique [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18] . La plus grande série a été décrite par Bisceglia 1 et comprenait 10 patients.…”

Section: Discussionunclassified

“…La plus grande série a été décrite par Bisceglia 1 et comprenait 10 patients. L'âge moyen au moment du diagnostic était de 48 ans (27-67 ans); on a signalé un seul cas chez un enfant, âgé de 12 ans 5 . Une prédo-minance féminine a été notée (5 femmes pour 2 hommes).…”

Section: Discussionunclassified

Adénome surrénalien à cellules oncocytaires

Hellara

Mouni

Touffahi

et al. 2008

CUAJ

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Les tumeurs surrénaliennes bénignes constituent une entité anatomopathologique souvent de découverte fortuite. Les cas d’oncocytome surrénali en sont très rares. Nous décrivons ici un cas de fortuitome surrénalien chez une femme de 37 ans, sans antécédents pathologiques, examinée par échographie abdominale en raison d’une douleur au niveau de la fosse iliaque droite. L’échographie abdominale a révélé une masse de la loge surrénalienne de 7 cm par 6 cm, bien délimitée, de densité tissulaire et absorbant faiblement le produit de contraste après injection. Le bilan hormonal est normal. L’étude anatomopathologique de la pièce prélevée par surrénalectomie a permis d’en arriverà un diagnostic d’adénome surrénali en à cellules oncocytaires. Les auteurs passent en revue la littérature sur cette pathologie rare, afin de mieux connaître son épidémiologie et ses modalités thérapeutiques.

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Adrenocortical oncocytoma in a child

Cited by 33 publications

References 17 publications

Adrenal Oncocytic Neoplasm: A Systematic Review

Adrenal Oncocytic Neoplasm: A Systematic Review

The first laparoscopic resection of an aldosterone-secreting adrenocortical oncocytoma in a child

Adénome surrénalien à cellules oncocytaires

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