Adrenocortical carcinoma with multiple liver metastases controlled by bland transarterial embolization and surgery resulting in long-term survival

Watanabe, Kiichi; Kodama, Yoshihisa; Sakurai, Yasuo; Yamaguchi, Beni; Yamasaki, Koji; Ishiguro, Atsushi; Ambo, Yoshiyasu

doi:10.1016/j.radcr.2022.01.052

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“…Liver metastasis is strongly associated with prognosis in ACC, and the control of liver metastasis is associated with a prolonged prognosis. 14 A multidisciplinary therapy that combines systemic chemotherapy with local treatment of metastatic lesions is important. 15 Surgical resection alone is often reported to be useful for the treatment of liver metastases.…”

Section: Discussionmentioning

confidence: 99%

A Case of Adrenocortical Carcinoma With a Favorable Tumor Control by Radiofrequency Ablation for Liver Metastasis

Kitsugi,

Kawata,

Kakizawa

et al. 2023

Journal of Investigative Medicine High Impact Case Reports

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A 57-year-old woman was diagnosed with adrenocortical carcinoma. Following the adrenalectomy, she underwent adjuvant radiation and mitotane therapy; however, liver metastases were observed. Repeated radiofrequency ablation (RFA) was performed for liver metastases. In addition, a multidisciplinary approach combining systemic chemotherapy, radiotherapy, and surgery was used for lung and distant lymph node metastases that arose during the course of treatment. Notably, 49 months have passed since the adrenalectomy and 36 months since the recurrence of the liver metastases, and the patient remains on multidisciplinary therapy. Thus, RFA for liver metastasis of adrenocortical carcinoma may be an effective component of a multidisciplinary treatment.

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Section: Discussionmentioning

confidence: 99%