Adrenergic receptors blockade alleviates dexamethasone-induced neurotoxicity in adult male Wistar rats: Distinct effects on β-arrestin2 expression and molecular markers of neural injury
Rasha M. S. M. Mohamed,
Enssaf Ahmad Ahmad,
Dalia M. Amin
et al.
Abstract:Background
Dexamethasone-induced neurotoxicity has been previously reported. However, the molecular mechanisms are still not completely understood.
Objectives
The current work aimed to investigate the modulatory effects of α- and β-adrenergic receptors on dexamethasone-induced neurotoxicity in rats focused on changes in β-arrestin2 and molecular markers of neural injury in cerebral cortex.
Methods
Male Wistar rats w… Show more
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