Adrenal rest carcinoma in hilumof kidney

Goren, Eliahu; Engelberg, Isaac S.; Eidelman, A.

doi:10.1016/s0090-4295(05)80085-8

Cited by 22 publications

(34 citation statements)

References 7 publications

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“…Adrenal rests have been postulated to be formed by the separation of cortical fragments displaced by the migration of medullary elements from the sympathochromaffin tissue into the preformed cortical primordium (Goren et al 1991). The incidence of adrenal rests could be as high as 50% in children, but the lesion generally disappears within a few years of birth (Goren et al 1991).…”

Section: Introductionmentioning

confidence: 99%

“…The incidence of adrenal rests could be as high as 50% in children, but the lesion generally disappears within a few years of birth (Goren et al 1991).…”

Section: Introductionmentioning

confidence: 99%

“…Adrenal rests tumor are further uncommon and the great majority of clinically detected adrenal rest tumors are reported to be functioning (Goren et al 1991). Nonfunctioning adrenal rest tumors are less frequent and were discovered incidentally (Goren et al 1991).…”

Section: Introductionmentioning

confidence: 99%

“…Nonfunctioning adrenal rest tumors are less frequent and were discovered incidentally (Goren et al 1991). In addition, adrenocortical carcinoma is a rare tumor with incidence 0.5-2 per million population annually, and also an aggressive cancer with a poor prognosis with 32-45% 5-year overall survival (Icard et al 2001).…”

Section: Introductionmentioning

confidence: 99%

“…In addition, adrenocortical carcinoma is a rare tumor with incidence 0.5-2 per million population annually, and also an aggressive cancer with a poor prognosis with 32-45% 5-year overall survival (Icard et al 2001). Therefore, adrenocortical carcinoma presumed to be arising in adrenal rest is extremely rare (Goren et al 1991;Arai et al 2000;Akishima-Fukasawa et al 2011).…”

Section: Introductionmentioning

confidence: 99%

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Non-functioning Adrenocortical Carcinoma Arising in an Adrenal Rest: Immunohistochemical Study of an Adult Patient

Yokoyama

Adachi

Tsubouchi

et al. 2013

Tohoku J. Exp. Med.

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Adrenal rest is uncommon in adults, and usually represents a small lesion incidentally detected during surgery or autopsy. The adrenal rest can be detected anywhere along the path of embryonic migration of adrenal cortex, including celiac axis, genitals and broad ligament, and may be formed with the separation of cortical fragments by the migration of medullary elements from the sympathochromaffin tissue into the preformed cortical primordium. In addition, even primary adrenocortical carcinoma is a rare tumor with incidence 0.5-2 per million annually; therefore, adrenocortical carcinoma arising in adrenal rests is extremely rare. We encountered a patient with non-functioning ectopic adrenocortical carcinoma in retroperitoneum. A 34-year-old female presented with an incidentally discovered retroperitoneal mass revealed by abdominal ultrasound in her regular health examinations. She did not have any clinical abnormalities and underwent hand-assisted laparoscopic resection of the tumor. A dark-brown tumor, measuring 65×56×45 mm, was identified in the retroperitoneal space between lower pole of right kidney and inferior vena cava. Histologically, the tumor was predominantly composed of compact eosinophilic cells forming nest-like arrangements and diffusely positive for the steroidogenic factor-1. The tumor met four of the criteria of Weiss used in histological diagnosis of adrenocortical carcinoma (eosinophillic cytoplasm, nuclear atypia, atypical mitosis, and sinusoidal invasion). The tumor cells were immunohistochemically positive for 17α -hydroxylase, dehydroepiandrosterone sulfotransferase and 3β-hydroxysteroid dehydrogenase, each of which is involved in the synthesis of adrenocortical steroids. Therefore, based on these findings, we diagnosed this tumor as ectopic adrenocortical carcinoma arising in adrenal rest of retroperitoneum.

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Section: Introductionmentioning

confidence: 99%

“…The incidence of adrenal rests could be as high as 50% in children, but the lesion generally disappears within a few years of birth (Goren et al 1991).…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Non-functioning Adrenocortical Carcinoma Arising in an Adrenal Rest: Immunohistochemical Study of an Adult Patient

Yokoyama

Adachi

Tsubouchi

et al. 2013

Tohoku J. Exp. Med.

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Ectopic aldosteronoma associated to another adrenocortical adenoma in the adrenal gland of the same side

Mazza¹,

Papotti

Durando

et al. 1995

J Endocrinol Invest

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The occurrence of tumors originating from aberrant adrenocortical tissue in ectopic site is very rare. Up to now only two cases of ectopic aldosterone-producing adenoma have been described. We have observed another case of ectopic aldosteronoma, located in the retrocaval region, laterally to the body of the 12th thoracic vertebra. This ectopic tumor was associated to another adrenocortical adenoma, in the adrenal gland of the same side. The diagnostic implications of this observation are discussed.

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Adrenal ectopy of adult groin region: a systematic review of an unexpected anatomopathologic diagnosis

Senescende¹,

Bitolog²,

E³

et al. 2016

Hernia

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Adrenal rest carcinoma in hilumof kidney

Cited by 22 publications

References 7 publications

Non-functioning Adrenocortical Carcinoma Arising in an Adrenal Rest: Immunohistochemical Study of an Adult Patient

Non-functioning Adrenocortical Carcinoma Arising in an Adrenal Rest: Immunohistochemical Study of an Adult Patient

Ectopic aldosteronoma associated to another adrenocortical adenoma in the adrenal gland of the same side

Adrenal ectopy of adult groin region: a systematic review of an unexpected anatomopathologic diagnosis

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