Adrenal myelolipoma

Kabbani, Ayla Al; Cuete, David

doi:10.53347/rid-43401

Cited by 1 publication

(2 citation statements)

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“…The diagnosis of myelolipoma is based on a combination of ultrasonographic [29,30], cytologic and histopathological findings [31,32]. Differential diagnoses for myelolipoma include extramedullary haematopoiesis (EMH), osseous metaplasia, angiomyelolipoma and angiomyomyelolipoma, lipoma and liposarcoma [5]. Macroscopically, myelolipomas are usually single [28,33], but multiple lesions in the same organ [14,17,22,23] or multicentric myelolipoma [18] have been described in some species.…”

Section: Discussionmentioning

confidence: 99%

“…The etiopathogenesis of myelolipomas is uncertain as it is not clear whether they represent true neoplasms or rather metaplasia (reversible transformation of one differentiated cell type into another due to chronic hormonal stimulation, or chronic inflammatory responses as a result of injuries that involve necrosis, stress or infection), hamartomas (benign-appearing masses composed of cells indigenous to the particular site resulting from aberrant differentiation) or choristomas (normal tissue, for example hematopoietic stem cells, misplaced during embryogenesis) [4,5].…”

Section: Introductionmentioning

confidence: 99%

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Splenic Myelolipomas in the Domestic Cat – to Operate or Not to Operate?

Kennedy,

Ferreira,

Dobromylskyj

et al. 2024

Preprint

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Myelolipoma is a benign, typically inert neoplasm of uncertain aetiology that is rarely reported in cats. Although commonly asymptomatic, in some cases, myelolipomas can cause abdominal discomfort or present with rupture and haemorrhage. Here, we describe a rare case of a splenic myelolipoma in a Domestic Long Hair cat in which, after extensive diagnostic investigations, clinical signs of hyporexia and weight loss were attributable to the presence of an intra-abdominal mass. The patient was treated by splenectomy and unexpectedly died during the post-operative period. Although splenectomy appears to be a sensible intervention in symptomatic patients, the optimal management of splenic myelolipomas in cats remains unknown. The risk-benefit ratio of surgical management needs to be carefully considered, and therapeutic intervention should be tailored individually to each patient.

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