Adrenal insufficiency due to the development of bilateral adrenal haemorrhage following hip replacement surgery

Mudenha, Emily T; Rathi, Manjusha

doi:10.1177/2054270415609837

Cited by 5 publications

(3 citation statements)

References 8 publications

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“…Similarly, Lundstrom et al described a case of BAH in a postoperative patient with a history of prior glucocorticoid use [ 8 ]. Similarly, Mudenha et al described various risk factors for non-traumatic BAH including exogenous steroids [ 9 ].…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Bilateral Adrenal Hemorrhage

Fatima

Tariq

Khan

et al. 2018

Cureus

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Bilateral adrenal hemorrhage (BAH) is a rare but potentially fatal entity that carries a mortality rate of 15%. Most cases are associated with sepsis, antiphospholipid syndrome, the use of anticoagulants, as well as trauma and surgery. In this case report, we present a case of BAH in a previously healthy man with a recent history of corticosteroid use. Our case emphasizes the ambiguous clinical presentation of BAH, which poses a challenge in the establishment of a correct diagnosis. We also illustrate the pathophysiology, diagnosis, and subsequent therapeutic approach to this rare clinical entity.

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Section: Discussionmentioning

confidence: 99%

A Rare Case of Bilateral Adrenal Hemorrhage

Fatima

Tariq

Khan

et al. 2018

Cureus

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“…Se ha relacionado con diversas entidades, en particular, con infecciones en el contexto del síndrome de Waterhouse-Friderichsen (1) . Otras etiologías importantes son la terapia anticoagulante con warfarina o heparina, principalmente (2,3) en el periodo posoperatorio, especialmente después de artroplastias y reemplazos articulares asociados con profilaxis antitrombótica con dosis bajas de heparina no fraccionada o heparinas de bajo peso molecular (1,4) . Otros factores descritos son las neoplasias como el feocromocitoma, metástasis, trauma, síndrome antifosfolípido (SAF), hipertensión, administración de ACTH, pancreatitis, quemaduras y el embarazo (2) .…”

Section: Introductionunclassified

Hemorragia adrenal bilateral sin insuficiencia adrenal asociada con enoxaparina.

Valencia

Corrales

Román-Gonzaléz

2020

Iatreia

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La hemorragia adrenal bilateral es un fenómeno poco común que puede acarrear consecuencias catastróficas por una crisis adrenal. Se ha asociado con diversas entidades como la sepsis, anticoagulación, neoplasias, el trauma, síndrome antifosfolípido y estado postoperatorio, especialmente, de cirugías ortopédicas. Su diagnóstico se dificulta en la medida en que los pacientes presentan signos y síntomas inespecíficos, por lo cual, una alta sospecha clínica es el principal indicador para la realización de una imagen que confirme el dictamen. Se presenta el caso de una hemorragia adrenal bilateral sin insuficiencia adrenal en una mujer de 71 años que, durante el quinto día del posoperatorio, tras una osteosíntesis de rodilla y recibiendo profilaxis antitrombótica con enoxaparina, ingresa al servicio de urgencias por dolor abdominal tipo cólico con 12 horas de evolución, acompañado de náuseas y sin signos de inestabilidad hemodinámica.

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“…that, if not recognized and treated promptly, have a high rate of mortality [5-8]. However, throughout the literature, there are rare but reported cases of non-infectious etiologies for bilateral adrenal hemorrhage, including in the postoperative setting or as a function of abnormalities of normal hemostasis [9-10].…”

Section: Introductionmentioning

confidence: 99%

Adrenal Hemorrhage in a Patient Anticoagulated with Apixaban with Antiphospholipid Syndrome

Sanford

Nanjundappa

Annie

et al. 2019

Cureus

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Atraumatic adrenal hemorrhage is a rare injury, often due to the disruption of normal hemostasis secondary to sepsis, autoimmune disease, or chronic anticoagulation. We present a case of recurrent adrenal hemorrhage in a patient with antiphospholipid syndrome previously maintained on warfarin for deep vein thrombosis and pulmonary embolism prophylaxis who worsened shortly after transition to apixaban therapy. Initial left-sided adrenal hemorrhage occurred four weeks after beginning apixaban, followed by the development of retinal hemorrhage and later right-sided adrenal hemorrhage. This is, to date, the first reported case of adrenal hemorrhage in a patient receiving chronic anticoagulation with apixaban.

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Adrenal insufficiency due to the development of bilateral adrenal haemorrhage following hip replacement surgery

Abstract: Bilateral adrenal haemorrhage should be considered as a differential diagnosis in patients presenting with non-specific symptoms and hypotension postoperatively.

Cited by 5 publications

References 8 publications

A Rare Case of Bilateral Adrenal Hemorrhage

A Rare Case of Bilateral Adrenal Hemorrhage

Hemorragia adrenal bilateral sin insuficiencia adrenal asociada con enoxaparina.

Adrenal Hemorrhage in a Patient Anticoagulated with Apixaban with Antiphospholipid Syndrome

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