Meta-analyses were performed on 25 comparative Minnesota Multiphasic Personality Inventory (MMPI) and MMPI-2 studies of 1,428 male African Americans versus 2,837 male European Americans, 12 studies of 1,053 female African Americans versus 1,470 female European Americans, and 13 studies of 500 male Latino Americans and 1,345 male European Americans. Aggregate effect sizes suggest higher scores for ethnic minority groups than for European Americans on some MMPI/MMPI-2 scales and lower scores on others. However, none of the aggregate effect sizes suggest substantive differences from either a statistical or clinical perspective. The MMPI and MMPI-2 apparently do not unfairly portray African Americans and Latinos as pathological. Effect sizes across studies generally did not vary as a function of sociodemographic variables, research setting, or use of the MMPI versus MMPI-2. It is recommended that additional between-and within-ethnic groups psychopathology research continue. In an increasingly multicultural society, ethnic differences in psychopathology could have far reaching implications. Perhaps the most benevolent implication of ethnic differences would be the need for culture-specific models of psychopathology, assessment, and treatment (Florsheim, Tolan, & Gorman-Smith, 1996; Okazaki, 1997). However, cultural differences have traditionally been regarded in our society as deficiencies (Jones, 1988). Ethnic differences in psychopathology could result in ethnic minority persons receiving different, and possibly negative, treatment in educational, employment, legal, mental health, and other settings in which measures of psychopathology are used to determine one's status. Thus, when ethnic differences in psychopathology are reported, the validity of such differences has been questioned (Okazaki & Sue, 1995b). Epidemiological data on psychopathology suggest few ethnic differences in rates of psychopathology. In the Epidemiological Catchment Area Project (ECAP), African Americans had significantly greater lifetime prevalence than European Americans only of simple phobia, agoraphobia, and cognitive impairment (Robins et al., 1984). In the same project, European Americans had a significantly greater prevalence of drug abuse and major depressive disorders than did Mexican Americans, but there were not 'significant differences for other disorders (Karno et al., 1987). More recent data also suggest comparable rates of psychopathology across ethnic groups (Huertin-Roberts, Snowden,