Admission hyponatremia in the elderly

Abstract

The authors studied the occurrence of admission hyponatremia and its association with selected patient and hospitalization characteristics and in-hospital mortality in a geriatric patient cohort (n = 4,123). Prevalence of admission hyponatremia was 3.5% and higher among women (4.6% vs 2.6%). In-hospital mortality was 16% for patients with admission hyponatremia versus 8.0% for patients without admission, hyponatremia. Adjusting for patient and hospitalization characteristics with a logistic regression analysis, admission hyponatremia was a significant independent predictor of mortality (RR = 1.95). Admission hyponatremia is associated with poor prognosis in the elderly hospitalized population.

Derivation and Validation of a Prognostic Model for Pulmonary Embolism

“…To derive our prediction rule, we used clinical variables routinely available at presentation that were previously shown to be associated with mortality in patients with PE or other acute diseases. These variables included demographics (12)(13)(14)(15), comorbid conditions (8,(12)(13)(14)16), physical examination findings (8,14,15,17,18), and laboratory and chest x-ray findings (8,14,16,(19)(20)(21)(22)(23)(24).…”

Hyponatremia in Postoperative Patients

“…A number of studies are available in literature assessing the risk of post-operative hyponatremia and its adverse effects [9,13,[16][17][18][19]. It was observed in the present study that post-operative hyponatremia can develop mostly in patients who are admitted in hospital with clinical diagnosis of peritonitis or abdominal trauma.…”

Hyponatraemia: new associations and new treatments

“…Severe hyponatraemia (!125 mmol/l) has been reported to be associated with in-hospital mortality of between 23 and 50% according to the plasma sodium concentration at presentation (17), and also with increased mortality at 6-month follow-up (11). Hyponatraemia has also been associated with increased mortality in the elderly (18), in heart failure (19), in pneumonia (20) and in intensive care patients (21). A recent paper presented data from a large cohort of 98 000 patients prospectively studied with outcomes measured up to 5 years after discharge from hospital.…”