Administration of hCG 5 days after Breeding and Reproductive Performance in Nulliparous Dairy Goats

Abstract

The objective of this study was to investigate the effect of hCG administration 5 days after breeding on plasma progesterone (P4) concentration and reproductive performance of oestrous-induced nulliparous dairy goats. A total of 59 nulliparous goats (36 Alpine and 23 Saanen) received intravaginal sponges with 60 mg medroxyprogesterone acetate for 9 days plus 200 IU equine chorionic gonadotrophin (eCG) and 22.5 microg d-cloprostenol 24 h before sponge removal. After detection of oestrus (day of oestrus = day 0) and breeding, 49 females were randomly assigned, according to the breed, into two treatments (T1 and T2). In T1 (n = 25) and T2 (n = 24), animals received intramuscular injection of 1 ml of saline solution (control) or 250 IU hCG, respectively, 5 days after breeding. Plasma P4 concentration (ng/ml) was determined from blood sampled on days 0, 5, 7, 13, 17, 21, 28 and 45 after breeding. Animals were scanned by transrectal ultrasound (5 MHz probe) on days 35 and 70 after breeding for detection of pregnancy. Plasma P4 concentration did not differ (p > 0.05) between treatments in all days, but it was increased (p < 0.05) in Saanen than in Alpine goats from days 13 to 45. Pregnancy and parturition rates, litter size and gestation period were similar (p > 0.05) to treatments and breeds. Results of this study indicate that human chorionic gonadotrophin (hCG) administration 5 days after breeding did not significantly alter reproductive performance in dairy nulliparous goats and that plasma P4 differed between Saanen and Alpine goats.

Estrous and ovulatory responses following cervical artificial insemination in Thai-native goats given a new or once-used controlled internal drug release with human chorionic gonadotropin

“…In ruminants, hCG has a wide range of applications. It is used for estrus synchronization in cattle (Schmitt et al 1996) and ovulation induction in sheep and goats (Wani et al 1997), also for overcoming the negative effect of premature regression of corpora lutea after superovulatory treatment in goats (Saharrea et al 1998), and for improving pregnancy rate in cattle and goats (Rajamahendran and Sianangama 1992;Fonseca and Torres 2005). Recently, a lower pregnancy rate was reported in large-size female sheep (40-50 kg of body weight) receiving three-time used CIDR devices in a short-term protocol (Vilarino et al 2013).…”

Different estrous induction protocols during the transition period in lactating turkish saanen does following Ai

“…Estrous appearance for the does occurred between 18 and 66 h after the end of treatment. The higher estrous response recorded during the 66 h observation period following the cessation of treatment (overall mean response 100%) was within the range of 83.1-89.5%, following treatment the intravaginal sponges containing MAP applied for 6 days or 9 days plus the intramuscular administration of eCG and PGF 2a 24 h before sponge removal Fonseca and Torres, 2005). The overall estrous response for the first 12±6 h period and within 66 h for three groups was 30.0% and 100%, respectively.…”

“…al., 2005;Lehloenya et. Recently, short-term progestagen treatments (6 to 9 days) in does has been shown to be as effective as long-term treatment to induce and synchronize estrus , the subsequent recorded fertility rate to was also high (Fonseca and Torres, 2005). Following treatment, a high percentage of does show estrus within a relative short time, but fertility rate is generally low or variable (Dogan et.…”

Production of Boer goat (Capra hircus) by nuclear transfer of cultured and cryopreserved fibroblast cells into slaughterhouse-derived oocytes

“…Sci., 54, 2009 (10): 448-460 Original Paper are needed to elucidate to what extent the origin of the oocyte affects the development of resultant reconstructed embryos into foetuses and possibly offspring in the goat. The administration of exogenous hormones like human chorionic gonadotropin (hCG) was used in cattle, sheep and goat (Fonseca and Torres, 2005). This hormonal administration can efficiently promote the ovulation of the first-wave dominant follicle forming the accessory corpus luteum.…”

“…The administration of exogenous hormones like human chorionic gonadotropin (hCG) was used in cattle, sheep and goat (Fonseca and Torres, 2005). This hormonal administration can efficiently promote the ovulation of the first-wave dominant follicle forming the accessory corpus luteum.…”