Administration of branched-chain amino acids to standardbred horses in training

Stefanon, Bruno; Bettini, Cristina; Guggia, Paolo

doi:10.1016/s0737-0806(00)80469-4

Cited by 19 publications

(11 citation statements)

References 19 publications

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“…This study aimed to describe the changes in the free AA pool of plasma and muscle and to estimate to which extend this pool can be influenced by a highly available protein/AA supplement. In this perspective, it differs from studies of Stefanon et al. (2000) and Casini et al.…”

Section: Discussionmentioning

confidence: 82%

“…Only a positive result obtained with Lys, and Thr mixture was reported by Graham‐Thiers and Kronfeld (2005). Extra BCAA did not improve performance according to Stefanon et al. (2000) and Casini et al.…”

Section: Discussionmentioning

confidence: 86%

“…Branched chain AAs mixtures were given to standardbreds in training (Casini et al., 2000; Stefanon et al., 2000), without clear effects on performance or metabolic parameters. However, these trials were focussed on the value of BCAAs as metabolic fuels and not on AA kinetics and changes in PD or protein synthesis (PS) in the recovery phase.…”

Section: Introductionmentioning

confidence: 99%

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Changes in intramuscular amino acid levels in submaximally exercised horses - a pilot study

Hoven¹,

Bauer²,

Hackl³

et al. 2009

Journal of Animal Physiology and Animal Nutrition

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The time-dependent changes in intramuscular amino acid (AA) levels caused by exercise and by feeding a protein/AA supplement were analysed in nine horses. Horses were submitted to a total of four standardized exercise tests (SETs). Amino acid concentrations were determined prior to, immediately after, 4 and 18 h after exercise. The experiment was subdivided into two consecutive periods of 3 weeks. In each period two SETs were performed. In the second period, horses were given a protein/AA supplement within 1 h after exercise. Significant changes in mean plasma AA levels similar to previous studies were noted to be time-dependent and to be associated with feeding the supplement. The intramuscular concentrations of the free AA in relation to pre-exercise levels showed significant time-dependent changes for alanine, asparagine, aspartate, citrulline, glutamine, glycine, isoleucine, leucine, methionine, serine, taurine, threonine, tyrosine and valine. Feeding the supplement significantly increased the 4 h post-exercise intramuscular concentration of alanine, isoleucine, methionine and tyrosine. At 18 h after exercise, apart from isoleucine and methionine, levels were still increased and also those of asparagine, histidine and valine in relation to none treatment. Hence, it was concluded that AA mixtures administered orally to horses within 1 h after exercise increased intramuscular AA pool.

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Section: Discussionmentioning

confidence: 82%

Section: Discussionmentioning

confidence: 86%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Changes in intramuscular amino acid levels in submaximally exercised horses - a pilot study

Hoven¹,

Bauer²,

Hackl³

et al. 2009

Journal of Animal Physiology and Animal Nutrition

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“…However, this study was based on few horses and did not consider any other AA than the BCAA. Branched‐chain amino acids supplementation led to higher post‐exercise levels of α‐keto‐isocaproate (a product of leucine degradation) in trotters, while lactate, glucose, allantoin and pyruvate concentrations were not affected (Stefanon et al., 2000). The authors suggested that BCAA supplements might have had only a weak effect on muscle energy metabolism or that the 10% increase of dietary AA might have been too low to give significant results (Stefanon et al., 2000).…”

Section: Introductionmentioning

confidence: 99%

“…Branched‐chain amino acids supplementation led to higher post‐exercise levels of α‐keto‐isocaproate (a product of leucine degradation) in trotters, while lactate, glucose, allantoin and pyruvate concentrations were not affected (Stefanon et al., 2000). The authors suggested that BCAA supplements might have had only a weak effect on muscle energy metabolism or that the 10% increase of dietary AA might have been too low to give significant results (Stefanon et al., 2000). Most studies have dealt with a limited spectrum of AA and a small number of horses and the information on changes that occurred in plasma‐free AA concentrations after defined levels of exercise was scarce.…”

Section: Introductionmentioning

confidence: 99%

The effects of short intensive exercise on plasma free amino acids in standardbred trotters

Hackl

Hoven

Zickl

et al. 2009

Animal Physiology Nutrition

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The aim of this study was to investigate the effect of short intense exercise on plasma amino acid concentrations in trotters and to test the repeatability of plasma amino acids concentration in samples obtained on two independent days under field conditions. Plasma amino acid concentrations were analysed in blood samples of 36 standardbred trotters before and after intense exercise over a distance of 2000 m. Sampling was repeated in 20 horses after 35 days. Exercise intensity was estimated from post-exercise lactate levels. Horses were divided in two groups according to a cut-off lactate concentration at 15 mmol/l. The plasma concentrations of alanine, aspartate, glutamate, isoleucine, leucine, lysine and taurine increased and arginine, asparagine, citrulline, glutamine, glycine, histidine, methionine, serine, tryptophan and 3-methylhistidine decreased after exercise. Ornithine, threonine, tyrosine, phenylalanine and valine concentrations remained constant. Higher intensity of exercise significantly decreased tryptophan and increased taurine concentrations. Sampling day had a significant effect on the absolute pre- and post-exercise amino acid concentrations. Exercise had a significant influence on the concentrations of most plasma amino acids in trotters. These changes could reflect shifts between the free amino acid compartments, but there were also some indications for muscle catabolism. The amino acid supply of sporting horses could be of specific significance for maintaining muscle integrity and for the improvement of post-exercise recovery of competition horses.

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Nutraceuticals in Equine Medicine

Sankaranarayanan¹

2019

Nutraceuticals in Veterinary Medicine

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Administration of branched-chain amino acids to standardbred horses in training

Cited by 19 publications

References 19 publications

Changes in intramuscular amino acid levels in submaximally exercised horses - a pilot study

Changes in intramuscular amino acid levels in submaximally exercised horses - a pilot study

The effects of short intensive exercise on plasma free amino acids in standardbred trotters

Nutraceuticals in Equine Medicine

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