Administration of 4% tetrasodium EDTA lock solution and central venous catheter complications in high‐risk pediatric patients with intestinal failure: A retrospective cohort study
Thomas I. Hirsch,
Scott C. Fligor,
Savas T. Tsikis
et al.
Abstract:BackgroundSelection of central venous catheter (CVC) lock solution impacts catheter mechanical complications and central line–associated bloodstream infections (CLABSIs) in pediatric patients with intestinal failure. Disadvantages of the current clinical standards, heparin and ethanol lock therapy (ELT), led to the discovery of new lock solutions. High‐risk pediatric patients with intestinal failure who lost access to ELT during a recent shortage were offered enrollment in a compassionate use trial with 4% tet… Show more
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