ADME Studies of Phytochemicals in Stachys pilifera Benth plant species

Abstract

Medicinal chemistry is a constantly changing and developing field. It is a successful and prosperous branch due to the new technologies, the changing complexities of medicine, and the expansion of medicinal chemistry knowledge. In drug design, many aspects need to be checked. The first step in drug development is discovering when new insights and technologies become available. Discovery is possible to find new treatments for diseases. This can begin with thousands of different computational methods, including under Computer-aided drug design (CADD). It provides a no. of tools and techniques that assist the various stages of drug design which can minimize the cost of drug research and development time. For this particular project, we use the SwissADME web tool it is a free web tool, easily assessable and convenient. It can characterize any chemical compound within a min. it allows you to compute physiochemical descriptors also to predict ADME parameters, pharmacokinetic properties, drug like nature of our compound, and medicinal chemistry friendliness of many small molecules to support drug discovery. For ADME analysis we chose a plant in which the isolation of its chemical compound is already done. i.e. stachys pilifera benth plant species. We did the ADME study of their chemical compounds using SwissADME and concluded its drug-like nature, its bioavailability, its synthetic accessibility, and many medicinal properties. We can say that Swiss ADME is the Asset for medicinal chemistry.