Adjuvant oral uracil and tegafur (UFT) improves survival after complete mesorectal excision (ME) for pathologic TNM stage III rectal cancer (RC): Results of the National Surgical Adjuvant Study (NSAS)-Colorectal Cancer (CC) 01 randomized trial

Aoki, Takayuki; Moriya, Yoshihiro; Yoshida, Shigeo; Shirao, Kuniaki; Ohashi, Yuko; Kodaira, Susumu

doi:10.1200/jco.2004.22.14_suppl.3524

Cited by 4 publications

(1 citation statement)

References 0 publications

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“…In this NSABP C-06 trial, the investigators concluded that /LV for patients with Stage II and III colon cancer. A randomized, Phase III trial of UFT adjuvant therapy compared with surgery alone for curatively resected rectal cancer was published in Japan. 51 In this NSAS-CC trial, UFT proved to be superior to surgery alone both in terms of DFS and of overall survival in an adjuvant setting. A meta-analysis of the effect of UFT on rectal cancer reconfirmed a significant benefit of adjuvant UFT therapy.…”

Section: Uft/lvmentioning

confidence: 94%

Efficacy of Oral Anticancer Agents for Colorectal Cancer

Sakamoto¹,

Oba²,

Matsui³

et al. 2006

Diseases of the Colon &Amp; Rectum

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Section: Uft/lvmentioning

confidence: 94%

Efficacy of Oral Anticancer Agents for Colorectal Cancer

Sakamoto¹,

Oba²,

Matsui³

et al. 2006

Diseases of the Colon &Amp; Rectum

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Promoting Health and Physical Function Among Cancer Survivors: Potential for Prevention and Questions That Remain

Demark‐Wahnefried

Pinto

Gritz

2006

JCO

201

150

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Cancer survivors are at increased risk, not only for progressive and recurrent disease, but also other cancers, cardiovascular disease, diabetes, osteoporosis, and functional decline. Lifestyle interventions to improve dietary and physical activity behaviors, and smoking cessation, have the potential to improve the overall health and quality of life of this vulnerable population. Studies on overall health and physical function from 1966 and beyond regarding the impact of behavioral interventions that used randomized and controlled designs were identified through MEDLINE and PubMed searches. Published reports currently exist for 22 exercise interventions, 11 diet-related interventions (excluding those limited to dietary supplements or single nutrients), two diet and exercise interventions, and 10 behavioral-based smoking cessation interventions. Although many interventions have been successful in promoting behavioral change and have resulted in improvements in various health-related outcomes, more research is needed to determine the key components of interventions that are able to produce the greatest behavioral change and the most favorable health-related benefits. The oncology care provider can play a pivotal role in improving the long-term health of cancer survivors by (1) being aware of opportunities to encourage healthful behaviors (ie, smoking cessation, weight control, and increased physical activity); (2) vigilantly tracking long-term effects among cancer survivors and exploring whether they are amenable to intervention; (3) staying abreast of current health behavior guidelines for cancer survivors and existing resources for professional and patient education; and (4) supporting and contributing to efforts aimed at primary and tertiary prevention research.

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