Abstract:Transmissible gastroenteritis (TGE), cause by transmissible gastroenteritis virus (TGEV), is an acute digestive and highly infectious disease in piglets. In this study, porcine interleukin-12 immunological adjuvant combined with a DNA vaccine bearing the TGEV-S1 gene was used to immunize piglets, and assessed the immune response of piglets. The results showed that CD4 + and CD8 + CD28 + T lymphocytes were significantly increased in immunized piglets compared to control groups. In addition, the observed increas… Show more
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