2015
DOI: 10.1590/s1677-5538.ibju.2015.0009
| View full text |Cite
|
Sign up to set email alerts
|

Abstract: Objectives:The objective of this study was to update the long-term outcome in the treatment of locally advanced upper tract urothelial carcinoma (UTUC) after radical nephroureterectomy (RNU) regarding the role of adjuvant chemotherapy.Materials and methods:Clinical data from 138 patients who underwent RNU for locally advanced UTUC (pT3/4 or pN+) were analyzed.Results:The adjuvant chemotherapy group comprised 66 patients, and other 72 patients did not receive adjuvant chemotherapy. Cisplatin-based chemotherapy … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

0
9
0

Year Published

2017
2017
2023
2023

Publication Types

Select...
8

Relationship

0
8

Authors

Journals

citations
Cited by 16 publications
(9 citation statements)
references
References 19 publications
0
9
0
Order By: Relevance
“…Kim et al . 8 also found no significant disease-specific or overall survival benefits associated with ACH in 138 patients who underwent RNU for locally advanced UTUC (pT3/4 or pN (+)). Conversely, Seisen and colleague evaluated 3,253 individuals with pT3/4 and/or pN (+) who received ACH or observation following RNU, and found that ACH was significantly associated with OS benefits in both the overall population (HR = 0.77) and all subgroups evaluated 11.…”
Section: Discussionmentioning
confidence: 85%
See 1 more Smart Citation
“…Kim et al . 8 also found no significant disease-specific or overall survival benefits associated with ACH in 138 patients who underwent RNU for locally advanced UTUC (pT3/4 or pN (+)). Conversely, Seisen and colleague evaluated 3,253 individuals with pT3/4 and/or pN (+) who received ACH or observation following RNU, and found that ACH was significantly associated with OS benefits in both the overall population (HR = 0.77) and all subgroups evaluated 11.…”
Section: Discussionmentioning
confidence: 85%
“…Thus, a definitive recommendation is unlikely until high-quality evidence from randomized prospective trials is obtained in patients with UTUC. Moreover, retrospective studies have shown conflicting results regarding the effects of ACH on oncological outcomes in patients with UTUC 8-11. In this regard, the role of ACH for patients with advanced stage UTUC remains an open question.…”
Section: Introductionmentioning
confidence: 99%
“…Of the 53 reports were retrieved for full-text evaluation. Only 16 studies met the inclusion criteria and were included in this systematic review [6,[13][14][15][16][17][18][19][20][21][22][23][24][25][26][27]. Table 1 showed the characteristics of the included studies.…”
Section: Studies Selectedmentioning
confidence: 99%
“…Risk of bias were moderate in 8 studies [18][19][20][21][22]24,26,27] and low in 7 studies [13][14][15][16][17]23,25]. The one RCT scored 3 in the Jadad scale [6] (Supplementary Materials Table S1, S2, Supplemental digital content 1, http://links.lww.…”
Section: Studies Selectedmentioning
confidence: 99%
“…19 in a Korean study by Kim et al, bladder cuffing was the sole independent prognostic factor for disease specific survival among patients with stage III or iv UTUc. 20 lughezzani et al evaluated the prognostic significance of BCE during RNU for cSS in a large-scale population-based cohort of patients with renal pelvic tumors. 12 They showed that there was no increase in cancer-related death in patients with localized (pT1-2n0/x) renal pelvic tumors when Bce was omitted and that cSS might decrease significantly if BCE was not performed in patients with locally advanced (pT3-4n0/x and pT[any]N1-3) renal pelvic tumors.…”
Section: Limitations Of the Studymentioning
confidence: 99%