“…Novel data showed clinical benefit with atezolizumab and bevacizumab as adjuvant therapy after curative interventions (eg, surgical resection or percutaneous ablation) for HCC tumors with high-risk features. [3] The IMbrave050 trial was the first phase III study to show the utility of adjuvant immunotherapy in those with high-risk HCC tumors, demonstrating a significant improvement in recurrence-free survival with atezolizumab and bevacizumab in comparison with active surveillance (HR 0.72 with p-value 0.012). [4] As such, the use of adjuvant immunotherapy in this setting was incorporated into the latest guidance statement from the American Association for the Study of Liver Diseases.…”