Adjunctive Surgical Management of Cutaneous Mycobacterium Fortuitum Infection

Madjar, David; Carvallo, Edward; Proper, Steven; Fenske, Neil A.

doi:10.1111/j.1524-4725.1985.tb01649.x

Cited by 17 publications

(3 citation statements)

References 11 publications

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“…However, the literature does clearly support early surgical debridement as a standard approach to these infections, along with targeted sensitivity-based antibiotic therapy. [17][18][19] These cases confirm that long-term targeted antibiotic therapy based on accurate, early sensitivities along with operative debridement as necessary can effect cure.…”

Section: Discussionsupporting

confidence: 51%

Breast Infections With Atypical Mycobacteria Following Reduction Mammaplasty

et al. 2010

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Reduction mammaplasty is one of the most common plastic surgery procedures performed in the US, with the goal of correcting symptomatic macromastia. More than 70,000 cases were performed in 2009, with few complications and low infection rates. The authors present two cases of breast infections with Mycobacterium fortuitum and one with Mycobacterium chelonei following bilateral reduction mammaplasty. Infection with these organisms is exceptionally rare following breast surgery in the absence of a prosthetic implant. All of the patients had a delayed presentation following complete wound healing and were refractory to first-line antibiotic therapy. All three required long-term antibiotics in consultation with an infectious disease specialist. The patients all required surgical drainage, and two patients also required formal operative debridement. All three patients eventually went on to complete wound healing.

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Section: Discussionsupporting

confidence: 51%

Breast Infections With Atypical Mycobacteria Following Reduction Mammaplasty

et al. 2010

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“…Besides MF, other relevant RGM's that are associated with SSI after aesthetic surgery are Mycobacterium Abcessus and Mycobacterium Chelonae [18]. Their treatment is similar and based on two pillars: proper surgical debridement and long-term, targeted, sensitivity-based antibiotic combination therapy [2,[24][25][26][27]. Surgical debridement is the first step of any kind of infection and is based on one main principle: source control.…”

Section: Discussionmentioning

confidence: 99%

Mycobacterium Fortuitum infection after abdominoplasty and breast reduction: case report, diagnostic tips and tricks, and overview of the current therapeutic consensus

Randy¹,

Assaf²,

Moustapha³

et al. 2019

Hyoid Bone Osteosarcoma: Report of a Case and Review of the Literature

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Background: Surgical site infections caused by non-tuberculous mycobacteria (NTM) are increasingly reported in the literature. Mycobacterium Fortuitum is the one that is most frequently associated with surgical site infections. Case Presentation: We present our first case of Mycobacterium Fortuitum infection after combined abdominoplasty and bilateral breast reduction. Discussion and Conclusions: Diagnosis of NTM-infections remains difficult. Typical symptoms are minor wound dehiscences with the evacuation of clear, odorless fluid collections. The onset can vary between one week to two years postoperatively. A wound dehiscence of a previously closed wound or slow healing of a wound must encourage a prompt diagnosis. A proper amount of fluid collection and/or tissue biopsy are necessary for an accurate diagnosis. Acid-fast or fluorochrome staining are also preferred over classic Gram staining. Treatment consists of proper surgical debridement and long-term, targeted, antibiotic combination therapy. Surgical debridement involves surgical drainage and removal of any infected foreign material. With regards to the antibiotic treatment, a dual antibiotic therapy, consisting of an oral Macrolide with initial parental therapy of Amikacin, is recommended. However, other combinations have been reported and also seem efficacious. An antibiotic treatment of four to six months is advised. The prognosis is usually favorable, although complete healing can sometimes be annoyingly long.

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“…Surgical debridement is also a mainstay of therapy, but only when effective antimicrobial therapy is also present 10 . Wound debridement in the absence of chemotherapy (that is, excision) can fail 11 …”

Section: Discussionmentioning

confidence: 99%

Mycobacterium Fortuitum Otitis Media

et al. 1997

Otolaryngol.--head neck surg.

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Although tuberculous infections of the ear are well reported in the scientific literature, infections with atypical mycobacteria are poorly represented. Nontuberculous mycobacterial isolates have become more common over the past few decades, and some reports have documented the emergence of these organisms at head and neck sites, t,2Mycobacterium fortuitum is a rapidly growing, Group IV organism that has been documented only twice in the otology literature of the United States. 3,4 We report a case of otomastoiditis caused by this organism and discuss the challenging treatment of this disorder in light of recent therapeutic developments. CASE REPORTA 14-year-old teenager came to the clinic complaining of otorrhea, which she had been experiencing for 5 days. She had had an episode of otorrhea the previous month. She had also received four sets of pressure equalizing tubes, the last at age 8 years, for recurrent otitis media. The patient was a competitive swimmer, swimming 3 miles a day, 6 days a week.An examination revealed otitis media and mild otitis externa with a pinpoint perforation in the anterior/superior quadrant that was only visible when a thick greenish-brown discharge was excreted with negative pressure. No tube was seen, and the left ear was normal. She was given amoxicillin and clavulanate orally and polymixin and neomycin drops topically. The patient did not experience any significant clinical improvement after l0 days, and her medication was changed to cefixime orally and a culture was obtained from her ear. No bacterial cultures grew, and her condition failed to improve. After 2 weeks of cefixime therapy, a pressure equalizing tube was placed in the right ear, and the oral antibiotics were changed to trimethoprim and sulfa. Her condition failed to improve after 14 days.Because of the failure of oral therapy, she was admitted to the hospital and was prescribed ampicillin and suIbactam. Her pressure equalizing tube, which had been placed 2 weeks previously, fell out around the time of admission and was From the Otolaryngology-Head and Neck Surgery Service (Dr.

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Adjunctive Surgical Management of Cutaneous Mycobacterium Fortuitum Infection

Cited by 17 publications

References 11 publications

Breast Infections With Atypical Mycobacteria Following Reduction Mammaplasty

Breast Infections With Atypical Mycobacteria Following Reduction Mammaplasty

Mycobacterium Fortuitum infection after abdominoplasty and breast reduction: case report, diagnostic tips and tricks, and overview of the current therapeutic consensus

Mycobacterium Fortuitum Otitis Media

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