Adjunctive Bright Light in Non‐Seasonal Major Depression

Martiny, Klaus

doi:10.1111/j.1600-0447.2004.00460_2.x

Cited by 88 publications

(64 citation statements)

References 56 publications

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“…10 Depressive symptoms are determined using both observer rating scales, such as the Hamilton Depression Rating Scale, and self-assessment of symptoms. 11 Few studies have compared artificial with natural light. However, in a study conducted in Switzerland, researchers compared the use of low-intensity artificial light, defined as half an hour of artificial light at 2,800 lux, with one hour of outdoor light.…”

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confidence: 99%

Residential Light and Risk for Depression and Falls: Results from the LARES Study of Eight European Cities

Brown

Jacobs

2011

Public Health Rep

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Objectives. We examined the relationship between self-reported inadequate residential natural light and risk for depression or falls among adults aged 18 years or older.Methods. Generalized estimating equations were used to calculate the odds of depression or falls in participants with self-reported inadequate natural residential light vs. those reporting adequate light (n6,017) using data from the World Health Organization's Large Analysis and Review of European Housing and Health Survey, a large cross-sectional study of housing and health in representative populations from eight European cities.Results. Participants reporting inadequate natural light in their dwellings were 1.4 times (95% confidence interval [CI] 1.2,1.7) as likely to report depression and 1.5 times (95% CI 1.2, 1.9) as likely to report a fall compared with those satisfied with their dwelling's light. After adjustment for major confounders, the likelihood of depression changed slightly, while the likelihood of a fall increased to 2.5 (95% CI 1.5, 4.2).Conclusion. Self-reported inadequate light in housing is independently associated with depression and falls. Increasing light in housing, a relatively inexpensive intervention, may improve two distinct health conditions.

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confidence: 99%

Residential Light and Risk for Depression and Falls: Results from the LARES Study of Eight European Cities

Brown

Jacobs

2011

Public Health Rep

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“…light therapy in chronic depression (Goel et al 2003 ;Terman, 2004) and bipolar depression (Benedetti et al 2004 a). The completion of the largest controlled, double-blind clinical trial to date of adjuvant bright light in non-seasonal major depression is auspicious (Martiny, 2004).…”

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confidence: 99%

“…The latest large controlled study compares 5 weeks of adjunctive bright white light with placebo dim red light in sertraline-treated patients with non-seasonal major depression (Martiny, 2004). With a response rate of 66 .…”

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confidence: 99%

Chronotherapeutics (light and wake therapy) in affective disorders

Wirz‐Justice¹,

Benedetti²,

Berger³

et al. 2005

Psychol. Med.

223

100

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The Committee on Chronotherapeutics was recently formed by the International Society for Affective Disorders (ISAD), which has asked us to provide a consensus review of chronotherapeutics (light and wake therapy) in affective disorders. We consider these non-pharmaceutical, biologically based therapies to be potentially powerful adjuvants ready for clinical application. We also stress the need for additional studies, both in-patient and out-patient, to broaden the evidence base for indications and efficacy.

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“…These studies varied greatly as to treatment modalities in regard to intensity, dosage, colour of light and length of light treatment. The results of these studies vary, but three reviews of light treatment [5,6,7] and two recent studies [8, 9] found a clear effect of adjunctive light treatment in non-seasonal major depression. Thus, both Martiny [9] and Benedetti et al [8] have demonstrated the effect of light therapy used as an adjunct treatment to enhance the response to sertraline and citalopram during the first weeks of treatment.…”

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confidence: 99%

Dose Response to Adjunctive Light Therapy in Citalopram-Treated Patients with Post-Stroke Depression

Søndergaard

Jarden

Martiny

et al. 2006

Psychother Psychosom

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Background:Post-stroke depression affects the outcome of stroke rehabilitation and is observed in approximately 30% of all stroke patients. We investigated whether the addition of light treatment to medical antidepressants influences the course of depression as measured by the Hamilton Depression Scale. Methods: The effect of a combination of light therapy and citalopram in stroke victims receiving citalopram was examined by use of two different doses of light therapy under double-blind conditions. Altogether, 63 patients were included in the study. The mean age was 74.9 years. Results: After 4 weeks of therapy, the 6-item subscale of the Hamilton Depression Scale showed a statistically significantly larger improvement in patients receiving high-intensity light treatment compared to those treated with medium-intensity light (p < 0.05). Conclusion: This pilot study demonstrates a dose response effect of light used as an adjunct therapy to antidepressants in post-stroke patients with major depression.

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Adjunctive Bright Light in Non‐Seasonal Major Depression

Abstract: The study results support the use of bright light as an adjunct treatment to antidepressants in non-seasonal depression.

Cited by 88 publications

References 56 publications

Residential Light and Risk for Depression and Falls: Results from the LARES Study of Eight European Cities

Residential Light and Risk for Depression and Falls: Results from the LARES Study of Eight European Cities

Chronotherapeutics (light and wake therapy) in affective disorders

Dose Response to Adjunctive Light Therapy in Citalopram-Treated Patients with Post-Stroke Depression

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