ObjectiveReaction time (RT) testing is one of the oldest diagnostic methods used in modern psychology, and is known as simple and sensitive cognitive test. It has been recently reported that RT is related to obesity in young, adult and elderly individuals. However, most of the studies included small sample of participants, used just body mass index (BMI) as body obesity index, and did not consider some potential confounders such as age, socioeconomic status and physical activity in their studies. Furthermore, there is little and contradictory results for children. Therefore, the present study aimed to examine the relationship between RT and weight status in a sample of children.MethodsThree hundred and fifty four 9–12 year old schoolboys underwent standard anthropometry, and various simple RT tests.ResultsAfter controlling for potential confounders no significant relationship was observed between audio-RT (RTA) and clinical RT (RTclin) with BMI, %fat, waist circumference (WC) and waist to height ratio (WHtR) (P > 0.05). But, significant relationship (β = 0.18; P = 0.02) was observed between visual-RT (RTV) and %fat (but not BMI, WC and WHtR).ConclusionsAmong the various simple RT tasks and central and total body obesity indices, just significant relationship was observed between %fat and RTV in the schoolboys. According to the results, it is concluded that RT impairment due to obesity may less be observed, or may not be observed for some types of RT tasks and obesity indices during childhood.