Adiposity has a greater impact on hypertension in lean than not-lean populations: a systematic review and meta-analysis

Arabshahi, Simin; Busingye, Doreen; Subasinghe, Asvini K; Evans, Roger G.; Riddell, Michaela A; Thrift, Amanda G.

doi:10.1007/s10654-014-9911-6

Cited by 21 publications

(11 citation statements)

References 54 publications

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“…The total percent body fat in the Ethiopian groups is lower than in south Asians with similar BMI, but the differences in body fat between urban and rural dwellers are of the order of magnitude shown to be significant for blood pressure changes in south Asians [32]. In lean populations relatively small changes in adiposity have a significant impact on blood pressure [33]. Thus, insulin resistance due to increased fat deposits may be one of several metabolic contributors (others as yet unidentified) to the increased blood pressure in the urban T1DM dwellers in northwest Ethiopia [33,34].…”

Section: Discussionmentioning

confidence: 86%

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Retinopathy in type 1 diabetes mellitus: Major differences between rural and urban dwellers in northwest Ethiopia

Alemu¹,

Dessie²,

Tsegaw³

et al. 2015

Diabetes Research and Clinical Practice

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Aim: To audit levels of diabetes-related eye disease in Type 1 diabetes mellitus (T1DM) patients in northwest Ethiopia. In particular to establish whether, despite identical clinical goals, major differences between the physically demanding life-style of rural subsistence farmers and the sedentary life-style of urban dwellers would influence the prevalence of diabetes-related eye complications.Methods: A robust infrastructure for chronic disease management that comprehensively includes all rural dwellers was a pre-requisite for the investigation. A total of 544 T1DM were examined, representing 80% of all T1DM patients under regular review at both the urban and rural clinics and representative of patient age and gender (62.1% male, 37.9% female) of T1DM patients from this region; all were supervised by the same clinical team. Eye examinations were performed for visual acuity, cataract and retinal changes (retinal photography). HbA1c levels and the presence or absence of hypertension were recorded.Results/Conclusions: Urban and rural groups had similar prevalences of severe visual impairment/blindness (7.0% urban, 5.2% rural) and cataract (7.3% urban, 7.1% rural). By contrast, urban dwellers had a significantly higher prevalence of retinopathy compared to rural patients, 16.1% and 5.0%, respectively (OR 2.9, p<0.02, after adjustment for duration, age, gender and hypertension). There was a 3-fold greater prevalence of hypertension in urban patients, whereas HbA1c levels were similar in the two groups. Since diabetic retinopathy is closely associated with microvascular disease and endothelial dysfunction, the possible influences of hypertension to increase and of sustained physical activity to reduce endothelial dysfunction are discussed.

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Section: Discussionmentioning

confidence: 86%

“…In lean populations relatively small changes in adiposity have a significant impact on blood pressure [33]. Thus, insulin resistance due to increased fat deposits may be one of several metabolic contributors (others as yet unidentified) to the increased blood pressure in the urban T1DM dwellers in northwest Ethiopia [33,34].…”

Section: Discussionmentioning

confidence: 99%

Retinopathy in type 1 diabetes mellitus: Major differences between rural and urban dwellers in northwest Ethiopia

Alemu¹,

Dessie²,

Tsegaw³

et al. 2015

Diabetes Research and Clinical Practice

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“…Este fato preocupante está incluído no "Plano de ação global para a prevenção e controle de doenças não transmissíveis 2013-2020" tendo como uma das metas até 2025 uma suspensão das taxas de obesidade no mundo em relação às do ano de 2010 21 . Em uma meta-análise realizada com estudos que utilizaram o IMC e a circunferência da cintura para verificar o impacto do excesso de peso na HAS, constatou que os homens obesos e os indivíduos com circunferência da cintura além do parâmetro desejável tinham mais chances para desenvolver hipertensão 22 , corroborando com estudos que relatam sobre o risco para resistência à insulina e aparecimento da diabetes tipo 2 19 .…”

Section: Discussionunclassified

A Qualidade De Vida De Idosos Com Obesidade Ou Sobrepeso

Souza

Bezerra²,

Fabrício

et al. 2018

RBCS

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Objetivo: avaliar a qualidade de vida de idosos com obesidade ou sobrepeso acompanhados na Atenção Primária à Saúde. Material e Métodos: estudo descritivo transversal, Os dados foram coletados no período de fevereiro a maio de 2016, na residência dos idosos utilizando para a coleta de dados um formulário sociodemográfico e clínico e um questionário específico desenvolvido pela Organização Mundial da Saúde para avaliar qualidade de vida em idosos – World Health Organization Quality of Life GroupOld. A amostra foi constituída de 27 idosos com obesidade ou sobrepeso Resultados: Os resultados sociodemográficos mostraram uma predominância do sexo feminino (81,48%), média de 69,70 anos (desvio-padrão= 7,33), baixa escolaridade (40,74%), casados (55,56%), negros (44,44%) e aposentados (74,04%). Pelas variáveis antropométricas a maioria das mulheres apresentava obesidade moderada (50%), em que 100% das idosas estavam com risco muito elevado relacionado a circunferência abdominal e 40% dos idosos estavam com risco muito elevado da circunferência abdominal e a maioria dos homens com sobrepeso (60%). A Relação Cintura Quadril mostrou que 86,36% das idosas estavam com valores >85 e 100% dos homens com valores >90. A maioria dos idosos apresentou uma qualidade de vida regular, com menos comprometimento nos domínios intimidade, autonomia, funcionamento do sensório e atividades passadas presentes e futuras e mais comprometimento nos de morte e morrer e participação social. Conclusão: a qualidade de vida encontrou-se afetada no contexto que envolve a finitude do ser e sua inserção e interação social. DESCRITORES Obesidade.Qualidade de Vida.Saúde do Idoso.Atenção Primária à Saúde.Sobrepeso.

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“…3–4 In addition, the process of frying foods could increase the concentration of oxidized cholesterol 5 through inhibition of paraoxonase enzyme activity. 6 Excess consumption of energy‐dense foods can lead to overweight, 7–8 with resulting elevated blood pressure 9 and development of diabetes, 10–11 3 risk factors for heart failure (HF). 12 Whereas consumption of fried foods has been associated with a higher risk of coronary heart disease (CHD) in the Nurses' Health Study (NHS) and the Health Professional Follow‐up Study (HPFS), 13 analysis of data from 40 000 adults in the Spanish cohort of the European Prospective Investigation into Cancer and Nutrition showed no association of fried food consumption with CHD.…”

Section: Introductionmentioning

confidence: 99%

Consumption of Fried Foods and Risk of Heart Failure in the Physicians' Health Study

Djoussé

Petrone

Gaziano

2015

JAHA

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Background Consumption of fried foods is highly prevalent in the Western dietary pattern. Though limited studies have reported a positive association between frequency of fried food intake and risk of coronary artery disease, diabetes, or hypertension, other investigators failed to report such an association. It is unclear whether intake of fried foods is associated with a higher risk of heart failure (HF). Hence, we sought to examine the association between the frequency of fried food consumption and the risk of HF. Methods and Results This was a prospective cohort study of 15 362 participants from the Physicians' Health Study. Fried food intake frequency was assessed by a food frequency questionnaire (1997–2001), and incident HF was captured by annual questionnaires. We used Cox regression to calculate hazard ratios (HRs) of HF. After an average follow‐up of 9.6±2.4 years, a total of 632 new HF cases occurred in this cohort. Compared to subjects who reported fried food consumption of <1 per week, HRs (95% CI) for HF were 1.24 (1.04 to 1.48), 1.28 (1.00 to 1.63), and 2.03 (1.37 to 3.02) for fried food intake of 1 to 3/week, 4 to 6/week, and 7+/week, respectively, after adjustment for age, energy intake, alcohol use, exercise, smoking, and overall diet score ( P linear trend, 0.0002). Similar results were obtained for intake of fried foods at home or away from home and among subjects with higher dietary score or HF without antecedent myocardial infarction. Conclusions Our data are consistent with a positive association of fried food intake frequency with incident HF in male physicians.

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Adiposity has a greater impact on hypertension in lean than not-lean populations: a systematic review and meta-analysis

Cited by 21 publications

References 54 publications

Retinopathy in type 1 diabetes mellitus: Major differences between rural and urban dwellers in northwest Ethiopia

Retinopathy in type 1 diabetes mellitus: Major differences between rural and urban dwellers in northwest Ethiopia

A Qualidade De Vida De Idosos Com Obesidade Ou Sobrepeso

Consumption of Fried Foods and Risk of Heart Failure in the Physicians' Health Study

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