Adiposity and blood pressure among 55 000 relatively lean rural adults in southwest of China

Abstract

Obesity is a strong determinant of blood pressure. Uncertainty remains, however, about which indices of adiposity most strongly predict blood pressure, particularly among those who were relatively lean, such as those from rural China. We analyzed cross-sectional data on 55 687 (38.3% men) participants aged 30–79 years who were enrolled into the China Kadoorie Biobank from a rural county in southwest of China during 2004–2008. Measured body mass index (BMI) and waist circumference (WC) were related to blood pressure in multivariable linear regression analyses. The overall mean values of BMI, WC, systolic blood pressure (SBP) and diastolic blood pressure (DBP) were 23.3 kg m−2, 78.0 cm, 129.2 mm Hg and 77.2 mm Hg, respectively. There was a strongly positive, and apparently linear, relationship of BMI and WC with blood pressure, with 1 s.d. higher BMI associated with 4.3/2.3 mm Hg higher SBP/DBP and 1 s.d. WC associated with 3.8/2.1 mm Hg (P<0.0001). Additional adjustment for WC only slightly attenuated the association of BMI with blood pressure, whereas additional adjustment for BMI almost completely eliminated the association of WC with blood pressure. Our findings suggest that in relatively lean Chinese adults, general adiposity is more strongly assciated with blood pressure than central adiposity.

Cross‐sectional, school‐based study of 14–19 year olds showed that raised blood pressure was associated with obesity and abdominal obesity

“…This is the most common cause of chronic liver disease in the United States and is strongly linked to metabolic risk factors, including diabetes, insulin resistance, dyslipidemia and metabolic syndrome . In this sense, subjects who have combinations of obesities during childhood and adolescence are more likely to be health outcomes during adulthood .…”

“…This is the most common cause of chronic liver disease in the United States and is strongly linked to metabolic risk factors, including diabetes, insulin resistance, dyslipidemia and metabolic syndrome (13). In this sense, subjects who have combinations of obesities during childhood and adolescence are more likely to be health outcomes during adulthood (6,17,26). Despite the strong evidence that there are many negative consequences of obesity, the term metabolic healthy obesity (MHO) emerged in the literature in 1982 (27,28).…”

“…The prevalence of childhood obesity has increased worldwide over the last decade , but may be levelling among children and adolescents . Nevertheless, this outcome still represents a major public health problem , as gaining weight has been directly associated with an increased probability of developing high blood pressure (HBP) and metabolic abnormalities , which is an established major risk factor for stroke, coronary heart disease and aortic stiffening in adulthood . Early detection and subsequent targeted prevention and intervention may reduce the life course burden associated with HBP .…”

Salt intake reduction strategies in the Eastern Mediterranean Region

“…However, dietary studies conducted in the Region showed that, as the nutrition transition unfolds, the consumption of potassium-rich foods such as wholegrain unsalted cereals, fruits and vegetables is decreasing, while the consumption of total fat, refined grains and high energy, nutrient-depleted foods is on the rise (47). Increases in body weight and adiposity, which are hallmarks of the nutrition transition, may also be contributing to further increases in blood pressure in countries of the Region (48,49).…”

Relación entre hipertensión arterial y obesidad central en madres de familia

“…El estudio realizado por Hernán-dez (2010), en el que se contrasta la CC con la PAD y PAS, presentó diferencias estadísticamente significativas entre los grupos de mujeres con obesidad abdominal y normales. De igual forma, en la investigación documentada por Chen (2015), la CC en las mujeres mostró fuerte y positiva asociación con la PAS. En el presente estudio, las madres de familia con obesidad abdominal exhibieron valores de tensión arterial más altos que las normales.…”