Adhesive retention dressings are more comfortable than alginate dressings on split-skin-graft donor sites

Hormbrey, E; Pandya, Aditya; Giele, Henk

doi:10.1016/s0007-1226(03)00195-4

Cited by 29 publications

(11 citation statements)

References 38 publications

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“…The donor sites are dressed with a single layer of adherent retention dressing (eg Mefix or Hyperfix), gauze and then a second layer of adherent dressing as described by Hombrey et al 8 Negative pressure wound dressings are not used. Splints are avoided, except when the grafted areas are over joint surfaces.…”

Section: Current Management Approachmentioning

confidence: 99%

The epidemiology and mortality of pretibial lacerations

Cahill

Gilleard

Weir

et al. 2015

Journal of Plastic, Reconstructive & Aesthetic Surgery

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Section: Current Management Approachmentioning

confidence: 99%

The epidemiology and mortality of pretibial lacerations

Cahill

Gilleard

Weir

et al. 2015

Journal of Plastic, Reconstructive & Aesthetic Surgery

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“…Ease of application and available resources/formularies are further aspects to consider. Many types of dressings have been studied for use in donor site wounds but none seem to fulfill all of these requirements ideally [2,3,4,5,6,7,8,9,10,11,12]. Furthermore, the results of these trials are not unanimous and sometimes even contradicting.…”

Section: Introductionmentioning

confidence: 99%

Management of Split-Thickness Skin Graft Donor Sites: A Randomized Controlled Trial of Calcium Alginate versus Polyurethane Film Dressing

et al. 2013

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Background: Split-thickness skin graft (STSG) donor sites sometimes cause more postoperative morbidity for patients than the wound covered with the graft. Yet, there is no consensus on which dressings are best suited to treat these donor sites. Objective: To evaluate two commonly used modern wound dressings in the postoperative healing of STSG donor sites in a prospective randomized controlled trial. Methods: 38 patients were randomly assigned to treatment of an STSG donor site with an alginate dressing or a polyurethane film dressing. The primary outcome measures were postoperative pain scores, secondary outcome variables were time to epithelialization, dressing changes and complications. Results: Postoperative pain on day 1 was significantly lower in the polyurethane film group (2.05 vs. 0.79, p = 0.035) as compared to the alginate group. This difference was not detected on day 5 (0.89 vs. 0.53, p = 0.52). Time to epithelialization did not differ significantly between the two dressing groups. There were more dressing changes in the polyurethane film group and problems with leakage. Conclusion: Whereas film dressings resulted in initially lower pain scores, alginate dressings caused fewer additional dressing changes and less leakage.

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“…Although subsiding with the use of some hydrocellular dressings, pain and discomfort almost always remained a problem during dressing replacement which is done imperatively in the first 48 hours and a week following the procedure [3,9,32]. The elevated cost per unit of the above mentioned dressing however becomes consequential relative to the wound surface to be covered [9,33,34].…”

Section: Discussionmentioning

confidence: 99%

Autologous keratinocyte suspension in platelet concentrate accelerates and enhances wound healing – a prospective randomized clinical trial on skin graft donor sites: platelet concentrate and keratinocytes on donor sites

Guerid

Darwiche

Berger

et al. 2013

Fibrogenesis Tissue Repair

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BackgroundWound healing involves complex mechanisms, which, if properly chaperoned, can enhance patient recovery. The abilities of platelets and keratinocytes may be harnessed in order to stimulate wound healing through the formation of platelet clots, the release of several growth factors and cytokines, and cell proliferation. The aim of the study was to test whether autologous keratinocyte suspensions in platelet concentrate would improve wound healing. The study was conducted at the Lausanne University Hospital, Switzerland in 45 patients, randomized to three different topical treatment groups: standard treatment serving as control, autologous platelet concentrate (PC) and keratinocytes suspended in autologous platelet concentrate (PC + K). Split thickness skin graft donor sites were chosen on the anterolateral thighs of patients undergoing plastic surgery for a variety of defects. Wound healing was assessed by the duration and quality of the healing process. Pain intensity was evaluated at day five.ResultsHealing time was reduced from 13.9 ± 0.5 days (mean ± SEM) in the control group to 7.2 ± 0.2 days in the PC group (P < 0.01). An addition of keratinocytes in suspension further reduced the healing time to 5.7 ± 0.2 days. Pain was reduced in both the PC and PC + K groups. Data showed a statistically detectable advantage of using PC + K over PC alone (P < 0.01).ConclusionThe results demonstrate the positive contribution of autologous platelets combined with keratinocytes in stimulating wound healing and reducing pain. This strikingly simple approach could have a significant impact on patient care, especially critically burned victims for whom time is of the essence.Clinical trial registry informationProtocol Record Identification Number: 132/03Registry URL: http://www.clinicaltrials.gov

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Adhesive retention dressings are more comfortable than alginate dressings on split-skin-graft donor sites

Cited by 29 publications

References 38 publications

The epidemiology and mortality of pretibial lacerations

The epidemiology and mortality of pretibial lacerations

Management of Split-Thickness Skin Graft Donor Sites: A Randomized Controlled Trial of Calcium Alginate versus Polyurethane Film Dressing

Autologous keratinocyte suspension in platelet concentrate accelerates and enhances wound healing – a prospective randomized clinical trial on skin graft donor sites: platelet concentrate and keratinocytes on donor sites

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