Adhesion ofPseudomonas aeruginosa,Achromobacter xylosoxidans,Delftia acidovorans,Stenotrophomonas maltophiliato contact lenses under the influence of an artificial tear solution

Dantam, Jaya; Subbaraman, Lakshman N.; Jones, Lyndon

doi:10.1080/08927014.2019.1710832

Cited by 12 publications

(7 citation statements)

References 84 publications

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“…There is limited available information regarding the inherent inhibition of pathogenic colonization provided by popular contact lens materials, but the OPTI-FREE products have previously been shown to be superior in reducing bacterial colonization on a lotrafilcon A lens [ 19 ]. Conversely, lenses made with senofilcon A have been shown to possess higher bacterial loads than competitive lenses in the same conditions [ 20 ]. However, the current study, combined with previous investigations [ 13 ], provides valuable real-world information regarding the disinfection efficacy of popular contact lenses when used with popular MPSs.…”

Section: Discussionmentioning

confidence: 99%

Antimicrobial Efficacy of Contact Lens Solutions Assessed by ISO Standards

et al. 2021

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Microbial keratitis (MK) is an eye infection caused by opportunistic bacteria or fungi, which may lead to sight-threatening corneal ulcers. These microorganisms can be introduced to the eye via improper contact lens usage or hygiene, or ineffective multipurpose solutions (MPSs) to disinfect daily wear contact lenses. Thus, the patient’s choice and use of these MPSs is a known risk factor for the development of MK. It is then critical to determine the efficacy of popular MPSs against ubiquitous ocular microorganisms. Therefore, we compare the efficacy of nine major MPSs on the global market against four different microorganism species, and with four different common contact lenses. In accordance with International Standards Organization protocol 14729 and 18259, the microorganisms were inoculated into each MPS with and without contact lenses, and held for the manufacturer’s disinfection time, 24 h, and 7 days after challenge with Serratia marcescens or Fusarium spp. Plates were incubated for 2–7 days and plate counts were conducted to determine the number of surviving microorganisms. The majority of MPSs demonstrated significantly higher disinfection efficacies without contact lenses. Broadly, among the microorganisms tested, the OPTI-FREE products (Puremoist, Express, and Replenish) maintained the highest disinfection efficacies at the manufacturer’s stated disinfection time when paired with any contact lens, compared with other MPSs. These were followed closely by RevitaLens and renu Advanced. MPSs containing dual biocides polyquaternium-1 and myristamidopropyl dimethylamine possessed the highest disinfection efficacy against multiple ocular pathogens.

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Section: Discussionmentioning

confidence: 99%

Antimicrobial Efficacy of Contact Lens Solutions Assessed by ISO Standards

et al. 2021

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“…A reduction in surface attachment over time during infection was also shown in sequential CF isolates, in association with the acquisition of mutations in genes with a presumptive role in surface adhesion [ 47 ]. However, some studies highlighted Achromobacter spp.’s ability to adhere on hydrogel contact lenses [ 48 , 49 ] and to form unattached or loosely attached aggregates held together by polysaccharides forming a peripheral shell around the bacterial cells [ 45 , 50 ]. Our current and previous [ 36 ] results confirm the poor adhesion ability of Achromobacter spp.…”

Section: Discussionmentioning

confidence: 99%

Adaptive Interactions of Achromobacter spp. with Pseudomonas aeruginosa in Cystic Fibrosis Chronic Lung Co-Infection

et al. 2021

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In the lungs of patients with cystic fibrosis (CF), the main pathogen Pseudomonas aeruginosa is often co-isolated with other microbes, likely engaging in inter-species interactions. In the case of chronic co-infections, this cohabitation can last for a long time and evolve over time, potentially contributing to the clinical outcome. Interactions involving the emerging pathogens Achromobacter spp. have only rarely been studied, reporting inhibition of P. aeruginosa biofilm formation. To evaluate the possible evolution of such interplay, we assessed the ability of Achromobacter spp. isolates to affect the biofilm formation of co-isolated P. aeruginosa strains during long-term chronic co-infections. We observed both competition and cohabitation. An Achromobacter sp. isolate secreted exoproducts interfering with the adhesion ability of a co-isolated P. aeruginosa strain and affected its biofilm formation. Conversely, a clonal Achromobacter sp. strain later isolated from the same patient, as well as two longitudinal strains from another patient, did not show similar competitive behavior against its P. aeruginosa co-isolates. Genetic variants supporting the higher virulence of the competitive Achromobacter sp. isolate were found in its genome. Our results confirm that both inter-species competition and cohabitation are represented during chronic co-infections in CF airways, and evolution of these interplays can happen even at the late stages of chronic infection.

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“…The issues that influence bacterial, viral, fungal and amoebic binding to contact lens materials are highly complex and variable, with confounding data on the factors that impact microbial binding [75][76][77][78][79][80]. To date, no studies have addressed this issue specifically for the virus that causes COVID-19.…”

Section: Contact Lens Materials Considerationsmentioning

confidence: 99%

The COVID-19 pandemic: Important considerations for contact lens practitioners

Jones

Walsh

Willcox

et al. 2020

Contact Lens and Anterior Eye

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104

113

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Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website.Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre -including this research content -immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Adhesion ofPseudomonas aeruginosa,Achromobacter xylosoxidans,Delftia acidovorans,Stenotrophomonas maltophiliato contact lenses under the influence of an artificial tear solution

Cited by 12 publications

References 84 publications

Antimicrobial Efficacy of Contact Lens Solutions Assessed by ISO Standards

Antimicrobial Efficacy of Contact Lens Solutions Assessed by ISO Standards

Adaptive Interactions of Achromobacter spp. with Pseudomonas aeruginosa in Cystic Fibrosis Chronic Lung Co-Infection

The COVID-19 pandemic: Important considerations for contact lens practitioners

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