Adherencia a la dieta mediterránea en pacientes afectos de glaucoma primario de ángulo abierto

Abreu-Reyes, J.A.; Álvarez-Luis, D.; Arteaga-Hernández, Víctor Javier; Sánchez-Mendez, M.; Abreu-González, R.

doi:10.1016/j.oftal.2016.12.002

Cited by 4 publications

(4 citation statements)

References 14 publications

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“…No significant association between adherence to the Mediterranean diet or the Dutch dietary guidelines and OAG or IOP was observed. One previous study reported moderate adherence to the Mediterranean diet in OAG patients; however, they could not address causality since exposure was not measured before onset of disease [ 60 ]. Another prospective cohort study reported a lower risk of glaucoma in participants adhering to a Mediterranean lifestyle, but no significant association was found with the Mediterranean diet in the single component analysis [ 61 ].…”

Section: Discussionmentioning

confidence: 99%

MIND diet lowers risk of open-angle glaucoma: the Rotterdam Study

et al. 2022

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Purpose To assess the association between the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet and the incidence of open-angle glaucoma (iOAG), as well as the association between iOAG and two other well-established diets in the Netherlands, i.e., the Mediterranean diet and Dutch dietary guidelines. Methods In the Rotterdam Study, participants were followed for iOAG since 1991, with intervals of approximately 5 years. A total of 170 participants developed iOAG during follow-up. Participants with iOAG were matched with healthy controls on age and sex in a case:control ratio of 1:5. The associations between food frequency questionnaire-derived diet adherences (baseline) and iOAG were analyzed using multivariable conditional logistic regression analyses. The associations between the diet adherences and intraocular pressure (IOP; a risk factor for OAG) were assessed using multivariable linear regression analyses. Results Greater adherence to the MIND diet was associated with a decreased iOAG risk (odds ratio [95% confidence interval]: 0.80 [0.66 to 0.96], for each 10-percent increase in adherence). Food component analyses showed that, in particular a higher intake of green leafy vegetables, berries and fish tended to be protective for iOAG. No significant associations were observed between adherence to the Mediterranean diet or Dutch dietary guidelines and iOAG. Moreover, none of the three examined diets were associated with IOP. Conclusion Adherence to the MIND diet was significantly associated with a lower incidence of OAG in contrast to adherence to the Mediterranean diet or the Dutch dietary guidelines. As this association was IOP-independent, the MIND diet may be particularly relevant for the prevention of neurodegeneration in the eye.

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Section: Discussionmentioning

confidence: 99%

MIND diet lowers risk of open-angle glaucoma: the Rotterdam Study

et al. 2022

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“…Regarding glaucoma, Abreu-Reyes et al [153] conducted an interesting observational study in the Spanish Canary Islands on the adherence to MedDiet in 100 patients with primary open-angle glaucoma (POAG). The authors reported moderate adherence to MedDiet in 71% of the subjects.…”

Section: Mediterranean Diet-current Knowledge On Eye Diseasesmentioning

confidence: 99%

“…Similarly, Chous et al [167] demonstrated an increase of visual acuity with no alteration of retinal thickness with the administration during 6 months to in type-1 and type-2 diabetic patients with no retinopathy or NPDR of DiVFuSS complex containing vitamins C, D3 and E, zinc oxide, eicosapentaenoic acid, docosahexaenoic acid, α-lipoic acid (racemic mixture), coenzyme Q10, mixed tocotrienols/tocopherols, zeaxanthin, lutein, benfotiamine, N-acetyl cysteine, grape seed extract, resveratrol, turmeric root extract, green tea leaf, and pycnogenol. The VSDR group performed a prospective case-control study in 575 participants during 38-month follow-up on the effects of the daily intake of a pill containing antioxidants, trace metals and ω3 fatty acids (Nutrof Omega ® formula), in T2DM patients, with and without DR and healthy controls, concluding that this course changes reduced the oxidative load in patients at risk of DR [40,153].…”

Section: Nutritional Supplementsmentioning

confidence: 99%

Searching for the Antioxidant, Anti-Inflammatory, and Neuroprotective Potential of Natural Food and Nutritional Supplements for Ocular Health in the Mediterranean Population

Valero-Velló

Peris-Martínez

García-Medina

et al. 2021

Foods

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Adherence to a healthy diet offers a valuable intervention to compete against the increasing cases of ocular diseases worldwide, such as dry eye disorders, myopia progression, cataracts, glaucoma, diabetic retinopathy, or age macular degeneration. Certain amounts of micronutrients must be daily provided for proper functioning of the visual system, such as vitamins, carotenoids, trace metals and omega-3 fatty acids. Among natural foods, the following have to be considered for boosting eye/vision health: fish, meat, eggs, nuts, legumes, citrus fruits, nuts, leafy green vegetables, orange-colored fruits/vegetables, olives-olive oil, and dairy products. Nutritional supplements have received much attention as potential tools for managing chronic-degenerative ocular diseases. A systematic search of PubMed, Web of Science, hand-searched publications and historical archives were performed by the professionals involved in this study, to include peer-reviewed articles in which natural food, nutrient content, and its potential relationship with ocular health. Five ophthalmologists and two researchers collected the characteristics, quality and suitability of the above studies. Finally, 177 publications from 1983 to 2021 were enclosed, mainly related to natural food, Mediterranean diet (MedDiet) and nutraceutic supplementation. For the first time, original studies with broccoli and tigernut (chufa de Valencia) regarding the ocular surface dysfunction, macular degeneration, diabetic retinopathy and glaucoma were enclosed. These can add value to the diet, counteract nutritional defects, and help in the early stages, as well as in the course of ophthalmic pathologies. The main purpose of this review, enclosed in the Special Issue “Health Benefits and Nutritional Quality of Fruits, Nuts and Vegetables,” is to identify directions for further research on the role of diet and nutrition in the eyes and vision, and the potential antioxidant, anti-inflammatory and neuroprotective effects of natural food (broccoli, saffron, tigernuts and walnuts), the Mediterranean Diet, and nutraceutic supplements that may supply a promising and highly affordable scenario for patients at risk of vision loss. This review work was designed and carried out by a multidisciplinary group involved in ophthalmology and ophthalmic research and especially in nutritional ophthalmology.

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“…The role of dietary components and dietary supplements in POAG has been widely investigated [51,52]. An observational study was conducted in the Spanish Canary Islands by Abreu et al [53] to assess the adherence to the MedDiet in 100 patients affected by POAG. Overall, mean percentages of adhesion to the MedDiet of POAG patients were moderate (71% of the cases).…”

Section: Neurotransmittersmentioning

confidence: 99%

Computational Analysis of Clinical and Molecular Markers and New Theranostic Possibilities in Primary Open-Angle Glaucoma

Pinazo-Durán

García-Medina

Bolarín

et al. 2020

JCM

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Primary open-angle glaucoma (POAG) is a paramount cause of irreversible visual disability worldwide. We focus on identifying clinical and molecular facts that may help elucidating the pathogenic mechanisms of the disease. By using ophthalmological approaches (biomicroscopy, ocular fundus, optical coherence tomography, and perimetry) and experimental tests (enzyme-linked immunosorbent assay (ELISA), high performance liquid chromatography (HPLC), and Western blot/immunoblotting) directed to evaluate the oxidative stress, inflammation, apoptosis, and neurodegeneration processes, we gather information to build a network of data to perform a computational bioinformatics analysis. Our results showed strong interaction of the above players and its downstream effectors in POAG pathogenesis. In conclusion, specific risk factors were identified, and molecules involved in multiple pathways were found in relation to anterior and posterior eye segment glaucoma changes, pointing to new theranostic challenges for better managing POAG progression.

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Adherencia a la dieta mediterránea en pacientes afectos de glaucoma primario de ángulo abierto

Cited by 4 publications

References 14 publications

MIND diet lowers risk of open-angle glaucoma: the Rotterdam Study

MIND diet lowers risk of open-angle glaucoma: the Rotterdam Study

Searching for the Antioxidant, Anti-Inflammatory, and Neuroprotective Potential of Natural Food and Nutritional Supplements for Ocular Health in the Mediterranean Population

Computational Analysis of Clinical and Molecular Markers and New Theranostic Possibilities in Primary Open-Angle Glaucoma

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