Adherence with immunosuppression in heart transplant recipients

Vitinius, Frank; Ziemke, Maria; Albert, Wolfgang

doi:10.1097/mot.0000000000000166

Cited by 6 publications

(3 citation statements)

References 21 publications

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“…Although official guidelines do not completely prohibit pet ownership, it should be kept in mind that pets pose a risk for zoonotic infections. 18,24–26 [33, 34] Although pets are also recognized as helpful for both psychological and physical health, there was no positive effect on mental or physical QOL of pet keeping in our study. Overall, in HTx recipients dietary restrictions and restrictions on pet keeping should not be neglected, and physicians should refer to these restrictions.…”

Section: Resultsmentioning

confidence: 69%

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Adherence of Heart Transplant Recipients to Prescribed Medication and Recommended Lifestyle Habits

et al. 2017

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Introduction: Nonadherence may cause severe health problems in heart transplant (HTx) recipients. Research Questions: The present study aimed to investigate adherence to prescribed medication and recommended lifestyle habits in post-HTx patients and to assess associations between adherence, quality of life (QOL), and psychological well-being. Design: A questionnaire package was sent to all HTx patients from our clinic (n ¼ 858) to answer questions anonymously on medication adherence, dietary recommendations (avoidance of raw animal products and ice cream), pet keeping (risk of zoonosis), anxiety and depression, QOL, and posttraumatic stress disorders. Results: Of the contacted patients, 524 (61%) responded and 505 fulfilled the inclusion criteria (age !18 years and ability to understand German). Of the study participants, 72.4% reported taking their medications very correctly, 72.2% stated consuming alcohol less often than once a week, 58.3% performed physical exercise at least once a week, one-third reported eating nonrecommended foods, 22.1% stated pet keeping, and 4.3% reported smoking. Adherence to prescribed medication was positively associated with age (P < .001) and mental QOL (P ¼ .015) but was unrelated to eating nonrecommended foods (P > .05). Depressiveness correlated inversely with physical QOL (r ¼ À0.232; P < .01) and mental QOL (r ¼ À0.411; P < .01). Stress disorders and minor stressful events were reported by 7.8% and 46.6%, respectively. Stress disorders correlated inversely with mental QOL (r ¼ À0.282; P < .01) and physical QOL (r ¼ À0.422; P < .01). Discussion: Many HTx patients adhere to prescribed medications and health advice. Nevertheless, nonadherence is a problem, especially in younger HTx patients, indicating the need for a nonadherence crisis intervention program for long-term HTx patients.

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Section: Resultsmentioning

confidence: 69%

“…Currently, there is a lack of behavioral intervention studies. 26 Unexpectedly, in our study group the young patients were confronted with traumatic events just as often as the older patients. This could overburden young people if no specific psychological treatment is offered.…”

Section: Clinical Impact and Future Prospectsmentioning

confidence: 63%

Adherence of Heart Transplant Recipients to Prescribed Medication and Recommended Lifestyle Habits

et al. 2017

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“…Although prospective, well‐powered studies to attendance in HTx, in general, are missing and demanded, 14 Helmy et al., as part of the prepandemic BRIGHT cohort study, 15 could show that medication nonattendance of immunosuppressants was 17%. To our knowledge, none of the current studies compared pre‐and pandemic nonattendance directly, and nonattendance was only investigated through medication intake.…”

Section: Discussionmentioning

confidence: 99%

COVID‐19 pandemic deteriorates aftercare attendance in heart transplant recipients independently of perceived impact on social life

Oehler

Bruno

Kelm

et al. 2022

Transplant Infectious Dis

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Background Heart transplant (HTx) recipients are at increased risk of developing infections or malignancies due to immunosuppressive medication. Thus, regular aftercare in those patients is of utmost importance. The extent of collateral damage due to the COVID‐19 pandemic (delayed or canceled clinical visits and diagnostics) on high‐risk patients is yet unknown. We believe that, especially for HTx‐patients, data acquisition on potential pandemic‐related non‐attendance is crucial to improve clinical care in the future. Therefore, we aim to decipher possible COVID‐19‐related alterations in attendance to clinical care post‐HTx using a survey‐based approach. Methods HTx recipients two years beyond transplantation were selected (n = 75). We filed a paper‐based questionnaire or an online survey containing nine items about COVID‐19 related exceptional circumstances. Fifty‐two patients (69%) returned fully answered questionnaires. Results A perceived impact on daily life was evident with 79% of all patients reporting moderate to severe negative influence of COVID‐19 pandemic on daily routine. We detected increased non‐attendance of clinical care during the COVID‐19 pandemic compared to pre‐pandemic time (38% vs. 6%, p<0.0001). The various diagnostic modalities of aftercare were heterogeneously affected, ranging from 2% non‐attendance for influence vaccination and 18% for colonoscopy. Off note, non‐attendance to clinical care within the pandemic was independent of perceived impact of the pandemia on daily life (p>0.68). Conclusions For the first time, we objectively demonstrate significant decrease in attendance to clinical care in HTx recipients during COVID‐19 pandemic. Efforts are needed to increase attendance in this highly vulnerable patient cohort. This article is protected by copyright. All rights reserved

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Post-transplant Psychosocial and Mental Health Care of the Cardiac Recipient

Shapiro

Pereira

Taylor

et al. 2018

Psychosocial Care of End-Stage Organ Disease and Transplant Patients

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Adherence with immunosuppression in heart transplant recipients

Abstract: There is a lack of behavioral intervention studies. So-called targeted interventions should be defined for clinical practice and research with randomized controlled studies.

Cited by 6 publications

References 21 publications

Adherence of Heart Transplant Recipients to Prescribed Medication and Recommended Lifestyle Habits

Adherence of Heart Transplant Recipients to Prescribed Medication and Recommended Lifestyle Habits

COVID‐19 pandemic deteriorates aftercare attendance in heart transplant recipients independently of perceived impact on social life

Post-transplant Psychosocial and Mental Health Care of the Cardiac Recipient

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