Adherence to HAART and its principal determinants in a cohort of Senegalese adults

Longitudinal Antiretroviral Adherence in HIV+ Ugandan Parents and Their Children Initiating HAART in the MTCT-Plus Family Treatment Model: Role of Depression in Declining Adherence Over Time

“…These high levels of adherence confirm findings in other resource-limited settings (Byakika-Tusiime et al 2005;Fong et al 2003;Landman et al 2003;Laniece et al 2003;Laurent et al 2004;Laurent et al 2005a, b;Nachega et al 2004;Orrell et al 2003;Oyugi et al 2004;Remien et al 2003;Weidle et al 2002;Weiser et al 2003). Our findings contrast with those of Merenstein et al (2008), who found an inverse relationship between adherence and the number of children in the family.…”

“…While most studies have shown high levels of adherence to ART in resource-constrained settings Bisson et al 2008;Byakika-Tusiime et al 2005;Diabate et al 2007;Etard et al 2007;Fong et al 2003;Landman et al 2003;Laniece et al 2003;Laurent et al 2004;Laurent et al 2005a, b;Mills et al 2006b;Nachega et al 2004;Orrell et al 2003;Oyugi et al 2004;Remien et al 2003;San Lio et al 2008;Tadios and Davey 2006;Weidle et al 2002;Weidle et al 2006;Weiser et al 2003) there has been little discussion about how HIV? women balance the demands of adherence to HIV ART, childcare, and antiretroviral adherence among their children who are HIV-infected.…”

Payment for antiretroviral drugs is associated with a higher rate of patients lost to follow-up than those offered free-of-charge therapy in Nairobi, Kenya

“…Finally, the association between end-user cost and adherence confirms observations from Senegal (Laniece et al, 2003), Uganda (Byakika-Tusiimi et al, 2005) and Botswana (Weiser et al, 2003;WHO, 2005b). Lack of compliance has immediate implications for the development of resistance to first-line ART regimens and leads to increased costs in the future, as second-line regimens cost five to ten times more than first-line regimens.…”

“…Secondly, from the perspective of sustainability, asking patients to pay for treatment adds up to minimal sums (at best to less than 10%) of overall costs incurred in providing HIV/AIDS care (Laniece et al, 2003). Sustainability can thus only be achieved through long-term commitments from governments that are supported by donors.…”

Résistance du VIH aux antirétroviraux

“…Des études récentes ont démontré que l'adhésion au traitement et la résistance virale aux ARV chez les patients de pays à faibles revenus n'est pas différente de celle observée chez les patients de pays mieux nantis [28][29][30][31]. Cependant, il est clair que l'efficacité de ces combinaisons thérapeutiques est conditionnée par la mise en place de programmes d'aide et d'intervention destinés à éviter l'apparition des phénomènes de résis-tance.…”