Adherence to guidelines for sensitivity analysis: cost-effectiveness analyses of dual oral antiplatelet therapy

Mauskopf, Josephine; Boye, Kristina S.; Schmitt, Claude; McCollam, PL; Birt, Julie; Juniper, Melissa D.; Bakhai, Ameet

doi:10.3111/13696990903123813

Cited by 3 publications

(4 citation statements)

References 35 publications

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“…[8][9][10] The frequency of retinal breaks in our patients who were taking AC (46%) was significantly lower than the frequency in our patients not taking AC (72%). However, this is still markedly higher than the 2-4% frequency in patients without VH.…”

Section: Discussionmentioning

confidence: 46%

“…Non-steroidal anti-inflammatory drugs (NSAIDs) also have antiplatelet properties, and their use has increased in the treatment of arthritis. [8][9][10][11][12][13][14][15][16][17][18][19] In this study, we examine the relationship between systemic anticoagulant and antiplatelet usage and the prevalence of retinal breaks and detachment in patients with VH in the setting of an acute PVD.…”

Section: Introductionmentioning

confidence: 99%

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Retinal tears after posterior vitreous detachment and vitreous hemorrhage in patients on systemic anticoagulants

El-Sanhouri

Foster

Petersen

et al. 2011

Eye

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Aims or Purpose To determine the rate of retinal tears (RTs) after posterior vitreous detachment (PVD) and vitreous hemorrhage (VH) in patients on systemic anticoagulants. Methods In all, 260 eyes of 260 patients with an acute PVD and VH were followed for evidence of an RT or detachment. Patients were divided into those taking systemic anticoagulants and those not taking anticoagulants. Results A total of 137 patients (53%) were taking anticoagulants, 123 (47%) were not. Overall, 72% of patients not taking any anticoagulant had evidence of an RT, whereas 46% of patients taking an anticoagulant had an RT (P-value 0.0002). Also, 37% of patients not taking an anticoagulant had a retinal detachment (RD), whereas 23% of patients taking any anticoagulant had an RD (P-value 0.01). Conclusions In patients with an acute PVD and VH using anticoagulants, RTs and RDs were common. Anticoagulation status may be an important contributing factor in predicting the incidence of an RT or detachment.

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Section: Discussionmentioning

confidence: 46%

Section: Introductionmentioning

confidence: 99%

Retinal tears after posterior vitreous detachment and vitreous hemorrhage in patients on systemic anticoagulants

El-Sanhouri

Foster

Petersen

et al. 2011

Eye

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“…These results were consistent with the existing literature. Mauskopf and colleagues [11] published a review of the cost-effectiveness of clopidogrel. Part of this review covered eight studies based on the Clopidogrel in Unstable Angina to Prevent Recurrent Events trial [12], including the York-clopidogrel model.…”

Section: Discussionmentioning

confidence: 98%

The CHD challenge: Comparing four cost-effectiveness models

et al. 2011

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We found that published guidance on methods was important to reduce variation in important model inputs. Although the comparison of models did not lead to consensus for all model inputs, it provided a better understanding of the reasons for these differences, and enhanced the transparency and credibility of all models. Similar comparisons would be aided by fuller publication of models, perhaps through detailed web appendices.

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“…Various clinical studies to compare the effectiveness of antiplatelet administration as a stroke prevention therapy have been carried out. Several studies have shown that single aspirin is more effective than clopidogrel [10,11]. Several trials have tested the efficacy and safety of clopidogrel and aspirin versus aspirin in preventing recurrent stroke in ischemic stroke [12][13][14].…”

Section: Introductionmentioning

confidence: 99%

Evaluating Economic Outcomes: Single-Use Aspirin vs. Aspirin-Clopidogrel in Ischemic Stroke Patients Based on Barthel Index Scores

Yosmar,

Febiana,

Fitria

2023

J Sains Farm Klin

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Ischemic stroke is a catastrophic disease that causes large costs in Indonesia. The high prevalence of stroke results in increased morbidity and mortality rates, which will impact the socioeconomic status of stroke patients. Cost Effectiveness Analysis (CEA) is a method in pharmaco-economics that aims to make decisions regarding the rational choice of therapy and evaluate the economic impact on ischemic stroke patients. This study aims to determine the Incremental Cost Effectiveness Ratio (ICER) value of antiplatelet therapy in the aspirin-clopidogrel combination group and the single aspirin group in ischemic stroke patients treated at the Regional General Hospital. Dr. M. Djamil Padang. The clinical parameter observed was the Barthel Index (BI) value. This research is a descriptive study with retrospective data collection using medical record data and the Hospital Management Information System (SIMRS) at RSUD Dr. M.Djamil Padang. The cost data shows the total direct medical costs incurred in treating ischemic stroke. Based on the results obtained, the Incremental Cost Effectiveness Ratio (ICER) value is IDR (-) 401,302. 71 per 1% increase. In this study it can be concluded that the aspirin-clopidogrel combination has better cost effectiveness than aspirin alone.

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Adherence to guidelines for sensitivity analysis: cost-effectiveness analyses of dual oral antiplatelet therapy

Cited by 3 publications

References 35 publications

Retinal tears after posterior vitreous detachment and vitreous hemorrhage in patients on systemic anticoagulants

Retinal tears after posterior vitreous detachment and vitreous hemorrhage in patients on systemic anticoagulants

The CHD challenge: Comparing four cost-effectiveness models

Evaluating Economic Outcomes: Single-Use Aspirin vs. Aspirin-Clopidogrel in Ischemic Stroke Patients Based on Barthel Index Scores

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