Adherence to Fish Oil Intervention in Patients With Chronic Kidney Disease

Zabel, Rachel; Ash, Susan; King, Neil; Bauer, Judy

doi:10.1053/j.jrn.2010.01.003

Cited by 2 publications

(1 citation statement)

References 8 publications

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“…CKD patients do not consume adequate dietary n -3 PUFAs [145]. Retention rates in clinical trials using fish oil pill interventions have a median of 97% [175] and there is good adherence to fish oil supplementation [189], indicating that this is a strategy that could be implemented in patients. However, Shapiro et al [134] recommend that the focus should be on increasing oily fish intake, rather than prescription of fish oil supplements, for cardioprotection in a population with diabetic nephropathy.…”

Section: Omega-3 Polyunsaturated Fatty Acids (N-3 Pufas)mentioning

confidence: 99%

Stirring the Pot: Can Dietary Modification Alleviate the Burden of CKD?

2017

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Diet is one of the largest modifiable risk factors for chronic kidney disease (CKD)-related death and disability. CKD is largely a progressive disease; however, it is increasingly appreciated that hallmarks of chronic kidney disease such as albuminuria can regress over time. The factors driving albuminuria resolution remain elusive. Since albuminuria is a strong risk factor for GFR loss, modifiable lifestyle factors that lead to an improvement in albuminuria would likely reduce the burden of CKD in high-risk individuals, such as patients with diabetes. Dietary therapy such as protein and sodium restriction has historically been used in the management of CKD. Evidence is emerging to indicate that other nutrients may influence kidney health, either through metabolic or haemodynamic pathways or via the modification of gut homeostasis. This review focuses on the role of diet in the pathogenesis and progression of CKD and discusses the latest findings related to the mechanisms of diet-induced kidney disease. It is possible that optimizing diet quality or restricting dietary intake could be harnessed as an adjunct therapy for CKD prevention or progression in susceptible individuals, thereby reducing the burden of CKD.

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