Adherence to combined Antiretroviral therapy (cART) among people living with HIV/AIDS in a Tertiary Hospital in Ilorin, Nigeria

Anyaike, Chukwuma; Atoyebi, Oladele Ademola; Musa, Omotoso Ibrahim; Bolarinwa, Oladimeji Akeem; Durowade, Kabir Adekunle; Ogundiran, Adeniyi; Babatunde, Oluwole Adeyemi

doi:10.11604/pamj.2019.32.10.7508

Cited by 24 publications

(23 citation statements)

References 37 publications

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“…The prevalence of adherence to ART in this study was 89.0%. This finding was lower than that conducted by [16] in Ilorin where the adherence prevalence was 92.6% as low lack of transportation money, travelling and avoiding being seen were the main factors given for non-adherence among them. However, [17] revealed higher prevalence 97.8% which was more than what this study reported.…”

Section: 'It Doesn't Stop Me From Taking My Drugs and After All I Didcontrasting

confidence: 76%

Socio-cultural Factors Influencing Adherence to Antiretroviral Therapy Among People Living with HIV/AIDS in a Tertiary Hospital in Southwestern Nigeria

Ademola¹,

Caroline²,

Ishola³

2019

IJHPEBS

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The study investigated the socio-cultural factors influencing adherence to antiretroviral drugs among people living with HIV in a University Teaching Hospital in Southwestern Nigeria. It investigated the influence of various socio-cultural factors on adherence of PLWHA to treatment regimen People Living with HIV/AIDS (PLWHA) of antiretroviral therapy (ART) in Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife and assessed the prevalence of adherence to ART among PLWHA in the study area. These were with the view to ascertaining the influence of socio-cultural factors in the PLWHA's adherence to antiretroviral therapy in the study location. The study design was a cross-sectional where both qualitative and quantitative research methods were adopted. The quantitative data were collected using structured questionnaire. The participants were HIV diagnosed patients attending clinic at the Obafemi Awolowo University Teaching Hospitals Complex in Ile-Ife where ages were between 18 and 60 years. Also two focus group discussion sessions were held with 10 males and 10 females living with HIV and currently on ART. Furthermore, in-depth interviews were conducted on three purposively selected healthcare givers (an experienced nurse, a doctor and a pharmacist) in the clinic. The quantitative data were analyzed using descriptive statistics such as tables and percentages and inferential statistics such as Chi Square and cross-tabulations. The qualitative data were analyzed in themes based on the objectives. The findings from the study indicated level of adherence to ART was 89.0% among the respondents. There was a statistically significant relationship (χ 2 = 22.14; p < 0.01) between social and family supports and the degree of adherence to ART among PLWHA. There was a statistically significant relationship between level of adherence and respondents' age (χ 2 = 66.05, p < 0.05). The older the respondents' age, the higher the level of adherence to ART. Also the relationship between educational level and adherence to ART was explored and found to be statistically significant (χ 2 = 26.04, p < 0.05). Adherence is inversely proportional to educational attainment. Nutrition, polygyny, difficulty in financing transportation fare to the clinic, unemployment, drug hawkers, religion, excuse duty from work and waking up very early were highlighted as socio-cultural barriers to adherence to ART. Fear of death, strong family support, religious belief, not seeking alternative treatment, absence of rituals and perceived improved health status were identified as very strong facilitators to adherence. The study concluded that socio-cultural factors exert very strong influences on PLWHA's adherence to antiretroviral therapy.

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Section: 'It Doesn't Stop Me From Taking My Drugs and After All I Didcontrasting

confidence: 76%

Socio-cultural Factors Influencing Adherence to Antiretroviral Therapy Among People Living with HIV/AIDS in a Tertiary Hospital in Southwestern Nigeria

Ademola¹,

Caroline²,

Ishola³

2019

IJHPEBS

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“…While [21] and [22] recorded the highest rate of non-adherence due to adverse drug effects at 66.7% and 76.7% out of 500 and 174 participants respectively. [21] argued that ascertaining the specific side effects experienced by the patients was difficult as the self-report given by these patients may have had some element of bias. In order words, there is a possibility that the patients may have provided a socially acceptable answer due to the sensitivity of the questionnaires thus providing incomplete responses.…”

Section: Resultsmentioning

confidence: 95%

Adverse Drug Effects and Non-Adherence to Antiretroviral Therapy in Nigeria: A Review

Okuku

Dan-Jumbo

2021

AJARR

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Objectives: This review aims to assess the link between adverse drug effects and non-adherence to antiretroviral therapy (ART) among people living with HIV/AIDS (PLWHA) in Nigeria. Methodology: Databases were searched namely PubMed, Web of science core collection, Science direct, Global Health (CABI) and MEDLINE. Fifteen (15) primary articles (studies carried out in Nigeria) met the inclusion criteria and were selected for the review. The primary articles selected for the review were analyzed and critiqued. Results: The articles selected for review showed that adverse drug effects is a barrier to adherence to ART. Conclusion: The review conclude that adverse drug effect is a barrier to adherence to ART among PLWHA in Nigeria and recommends patient education on side effects of ART, the need for regular exercises, eating healthy meals and the need for physicians to simplify the regimen with regards to the amount of medication to take and the timing.

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“…Adherence to ART by patients has continued to be suboptimal 2 which might be due to multi- factorial causes. Some of such factors reported in the literature include patient-related factors, inconvenient dosing frequency, pill burden, side effects, patient-health-care provider relationships, lack of money for transportation to the hospital, busy schedule, and forgetting 9 , 21 , 22 . Any factor that influences adherence to regimen should be a concern to health care providers.…”

Section: Introductionmentioning

confidence: 99%

Factors affecting adherence to anti-retroviral therapy among women attending HIV clinic of a tertiary health institution in SouthEastern, Nigeria

Opara¹,

Iheanacho²,

Nebo³

et al. 2022

Afr H. Sci.

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Background: Strictly adherence to antiretroviral therapy (ART) is needed to achieve viral suppression. Studies have focused on HIV positive pregnant women’s adherence. Factors affecting non-pregnant HIV positive women’s adherence has been understudied in Enugu Objective: The study objective was to identify factors affecting adherence to ART among HIV positive women attending retroviral clinic of a tertiary hospital in Enugu. Methods: Using a descriptive cross-sectional design, a pre-tested structured questionnaire was used for data collection among 286 HIV positive women aged 18 years and above. Data were analyzed using descriptive statistics of proportions, percentages, and means. Responses with a mean score of ≥2.5 were taken as important factor affecting adherence. Results: Overall adherence was 56.2%. Participants were considered adherent if they took ≥95% of their prescribed ART. Lack of transport fare (2.69 ±1.36), long-distance to clinic (2.82±1.26), health workers’ poor attitude (2.74±1.28), and lack of partners’ and parents’ support (2.57±1.05) affected adherence negatively while ease in renewing prescription and minimal side effects of drugs enhanced adherence. Enfuvirtide (21.1%) and Lamivudine (17.4%) were drugs that were mostlyskipped. Conclusions: Adherence to ART was low among the women attending the HIV clinic in Enugu. Adherence counseling and education should be provided before ART initiation. Strategies to reduce stigma, increase family support, and improve healthcare providers’ attitudes should be employed. Keywords: Adherence; anti-retroviral therapy; factors; women; HIV Clinic; Enugu.

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Adherence to combined Antiretroviral therapy (cART) among people living with HIV/AIDS in a Tertiary Hospital in Ilorin, Nigeria

Cited by 24 publications

References 37 publications

Socio-cultural Factors Influencing Adherence to Antiretroviral Therapy Among People Living with HIV/AIDS in a Tertiary Hospital in Southwestern Nigeria

Socio-cultural Factors Influencing Adherence to Antiretroviral Therapy Among People Living with HIV/AIDS in a Tertiary Hospital in Southwestern Nigeria

Adverse Drug Effects and Non-Adherence to Antiretroviral Therapy in Nigeria: A Review

Factors affecting adherence to anti-retroviral therapy among women attending HIV clinic of a tertiary health institution in SouthEastern, Nigeria

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