Adherence of Staphylococcus aureus to cultured epidermal cells during differentiation

Adherence of Staphylococcus intermedius to canine corneocytes in vitro

“…The greatest adherence has been demonstrated with terminally differentiated keratinized cells. 31 In contrast, Miyake et al 32 reported diversity of staphylococcal adherence to host cells in various stages of differentiation. Some of the isolates of S. aureus showed increased adherence to differentiated cultured epidermal cells, others adhered better to undifferentiated cells, and some did not show any preference.…”

“…The greatest adherence has been demonstrated with terminally differentiated keratinized cells 31 . In contrast, Miyake et al 32 . reported diversity of staphylococcal adherence to host cells in various stages of differentiation.…”

Atypical lipoteichoic acids of gram-positive bacteria

“…LTA has been described as the major cell wall component responsible for the surface hydrophobicity of group A streptococci (40), in which it mediates the adherence of the bacteria to fibronectin on epithelial cell surfaces (2). LTA may also influence the adherence of group B streptococci to epithelial cells (44,64), Staphylococcus saprophyticus to uroepithelial cells (63), Staphylococcus epidermidis to fibrin-platelet clots (9), and Staphylococcus aureus to mucosal, epithelial, and mesothelial cells (8,21,42), although protein seems to be the principal adhesin of S. aureus (2,19). Similarly, the strongly hydrophobic character of the B. bifidum subsp.…”

“…pennsylvanicum surface has been attributed to both the surface protein and the lipoglycan of this bacterium (46), and the lipoglycan has been implicated as an adhesin in the interaction of the bacterium with colonocytes (48). All macroamphiphiles have a comparable potential to contribute to surface hydrophobicity and to act as bridging ligands between bacteria and other surfaces, thereby contributing to the complex range of cooperative interaction likely to be required for adhesion (15,23,42,55). Studies of the critical micellar concentrations of LTA, which fall in the range from 0.28 to 0.69 ,uM (67) up to 5 ,uM (13), suggest that acylated monomeric LTA may represent a significant proportion of the extracellular LTA of some bacteria (67).…”

Conspicuous Ingestion of Staphylococcus aureus Organisms by Murine Fibroblasts In Vitro

“…Although the ingestion rate of strain 4203-II was similar to that of Cowan I strain, strains 4207-II and 4219-II revealed lower rates of ingestion than that of Cowan I strain. As S. aureus has been regarded as an extracellularly growing pathogen, many investigations have been made on the adherence of S. aureus to various host cells, including skin (7) and nasal (1) epidermal cells, peritoneal mesothelial cells (4) and keratinized epithelial cells (2). Some studies have been made concerning the ingestion of S. aureus organisms by host cells (3,5,6,(9)(10)(11) using various types of cells.…”