“…For instance, Tetz et al (17) proved in vitro that a S. epidermidis strain adhered less easily on heparinized than on untreated PMMA, but they failed to obtain the same result with another strain, thus suggesting a large disparity among bacteria, as far as heparinized implants are concerned. Similarly, when comparing two S. epidermidis strains having different surface properties, Schmidt et al (19) and Schloricke et al (20) found that the more hydrophobic strain bound to a lesser extent to heparinized PMMA than to untreated PMMA or silicone, whereas the more hydrophilic one adhered more strongly on the heparinized polymer. Therefore, the modification of polymer surfaces can result in rather variable effects, depending-among other factors-on the bacterial surface composition and properties.…”