Adherence in vitro of Candida albicans to plasma treated acrylic resin. Effect of plasma parameters, surface roughness and salivary pellicle

Abstract

Results demonstrated that ArO2/70W and ArSF6/70W plasma treatments showed promising potential for reducing the adherence of C. albicans to denture base resins.

Cold plasma-induced surface modification of heat-polymerized acrylic resin and prevention of early adherence of <i>Candida albicans </i>

“…Nurhaerani et al found that CF4 plasma was useful in inhibiting Streptococcus mutans adhesion on stainless steel surface 22) . Zamperini et al confirmed that ArO2/70W and ArSF6/70W plasma treatment groups showed significantly reduced Candida albicans biofilm adhesion than the control group after plasma treatment of heat-curing acrylic resin samples 23) . However, the early adherence of Candida albicans on plasma-treated, heat-polymerized acrylic resins is rarely investigated.…”

“…In the present study, saliva was used to better simulate Candida albicans adherence. Recent reports stated that salivary films neither influenced Candida albicans adhesion nor significantly altered surface free energy and its polar and dispersive components 23,24) . In this study, Ar/O2 plasma treatment caused a significant decrease in contact angle and Candida albicans adhesion (Figs.…”

“…Atmospheric-pressure cold plasma -a complex mixture composed of ions, energetic free radicals, electrons, atoms, and molecules generated by gas discharge-has attracted much interest in biomedicine because of its potential applicability in bacterial inactivation 13,14) , tooth whitening 15,16) , blood coagulation 17) , and cancer therapy 18) . In recent years, researchers reported that plasma could be used as an economical and effective means to modify dental materials' surfaces [19][20][21][22][23] . Previous researches confirmed that after heat-cured acrylic resin was treated with cold plasma, it increased the shear bond strength between heat-cured acrylic resin and self-curing acrylic resin 21) .…”

Effectiveness of disinfectants on the adherence of <i>Candida albicans</i> to denture base resins with different surface textures

“…Although some studies have suggested that the adhesion ability of yeasts to polymeric surfaces is modulated by hydrophobic forces, others found no correlation between hydrophobicity and Candida adhesion (8)(9)(10). It has also been reported that an increase in surface roughness enhances C. albicans retention (11)(12)(13)(14) as it increases the surface area and/or shear forces (5), thus allowing easier microbial attachment and difficult detachment even when the prosthesis has been cleaned with antimicrobial agents (10). However, most of these studies focused on the adherence of C. albicans to rough denture surfaces (3,(11)(12)(13), but failed to investigate the efficiency of antimicrobial agents in removing yeasts from these surfaces.…”

“…Candida albicans, which has the ability to adhere and proliferate on both soft and hard tissues (2), has been widely associated with the etiology of denture stomatitis (3,4). Since adherence of C. albicans to polymethyl methacrylate (PMMA) resin surfaces is an essential and necessary step for successful colonization and development of pathogenesis, (3) treatment of denture stomatitis should target reduction of initial fungal adherence (5).…”