Adherence and quality of care in IBD

Bager, Palle; Julsgaard, Mette; Vestergaard, Thea; Christensen, Lisbet Ambrosius; Dahlerup, Jens Frederik

doi:10.1080/00365521.2016.1195870

Cited by 29 publications

(19 citation statements)

References 27 publications

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“…The patient's involvement in the treatment selection led to higher confidence in the selected treatment option (second part of H2). 'The extent to which the patient's behaviour matches agreed recommendations from the prescriber' along with mutual agreement on treatment decisions refer to adherence [49,50]. Thus, involvement in treatment selection leads to higher decision certainty about the treatment, which fosters patient's adherence.…”

Section: Discussionmentioning

confidence: 99%

Patients’ perception of their involvement in shared treatment decision making: Key factors in the treatment of inflammatory bowel disease

Veilleux

Noiseux

Lachapelle

et al. 2018

Patient Education and Counseling

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Section: Discussionmentioning

confidence: 99%

Patients’ perception of their involvement in shared treatment decision making: Key factors in the treatment of inflammatory bowel disease

Veilleux

Noiseux

Lachapelle

et al. 2018

Patient Education and Counseling

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“…In a multicenter, prospective cohort study including 1,558 patients with CD and 1,054 patients with UC, younger age at diagnosis, flares, feelings of anxiety or depression, and nonadherence were associated with future nonadherence to treatment [13]. A recent study from Bager et al [2] reported young age and smoking as predictors of nonadherence, while high adherence rates were explained by high patient satisfaction and high degree of shared decision making. A very recent study published by Keil et al [14] conducted in 198 outpatients with a diagnosis of UC has shown that the patient’s education level can significantly influence compliance to treatment.…”

Section: Introductionmentioning

confidence: 99%

“…Treatment of the disease is symptomatic, and adherence to treatment has an impact on the course of the disease [2]. Medical treatment is required to induce and maintain remission of IBD, and adherence to treatment has been associated with positive treatment outcomes [3-5].…”

Section: Introductionmentioning

confidence: 99%

Patient Preference and Physician Perceptions of Patient Preference for Oral Pharmaceutical Formulations: Results from a Real-Life Survey

et al. 2018

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Background: Pharmaceutical treatment prescribed according to patient preference for a formulation may have a positive impact on adherence to treatment and consequently on treatment outcomes. Aim: This study aimed at understanding patient preference for pharmaceutical formulations and attributes that trigger patient preference and physician perception of patient preference. Methods: Between August and September 2017, gastroenterologists and patients with mild to moderate ulcerative colitis from France, Germany, Spain, and the UK participated in an online survey. The investigation was exploratory in nature, and descriptive results are presented. Results: Patient (n = 380) preference appears to be driven by the appearance (format, shape, size, and color – 44%), number of units per administration (39%), and number of administrations per day (17%). Gastroenterologist (n = 159) preference is instead driven by the number of administrations per day (55%), number of units per day (26%), and tablet size (19%). Overall, 254 (67%) patients preferred a tablet formulation, 111 (29%) preferred granules, and 15 (4%) other formulations. According to gastroenterologist perception of patient preference, only 49% of patients prefer tablets, 38% prefer granules, and 13% have no preference. After switching from granules to tablets, 25% patients expressed negative feelings for granules. However, after switching from tablets to granules, 44% of patients still have positive perceptions of tablets. Among patients receiving tablets (n = 255), 18 (7%) perceived their treatment to be not at all effective versus 16 (13%) patients receiving granules (n = 125). A similar proportion of patients in the two groups perceived their treatment as extremely effective (48 vs. 46%, respectively). Conclusions: Patients generally prefer tablets. Patient and gastroenterologist perception of patient preference for different oral drug formulations is triggered by the same attributes but with inverse importance. To improve adherence, patients should be involved in the choice of the treatment formulation.

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“…After univariate and multivariate analyses, perception of ease in contacting the gastroenterologist in case of need was a protective factor for inadequate adherence to both oral 5-aminosalicylates and thiopurines. Quality of care and high patient satisfaction have previously been linked with high treatment adherence rates in IBD patients [32]. This finding underscores the importance of IBD nurses in the IBD multidisciplinary team, in which one of their key role is accessible care [33].…”

Section: Discussionmentioning

confidence: 74%

Treatment Adherence in Inflammatory Bowel Disease Patients from Argentina: A Multicenter Study

Lasa

Correa

Fuxman

et al. 2020

Gastroenterology Research and Practice

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Background and Aim. Treatment adherence is a frequent problem in inflammatory bowel disease (IBD). No study has assessed adherence in Argentinian patients with IBD. The aim of this study was to determine inadequate adherence to oral and parenteral therapies in patients with IBD from Argentina and to identify factors associated with it. Methods. A multicenter cross-sectional study involving seven referral centers from three cities of Argentina was undertaken. Patients with a diagnosis of ulcerative colitis (UC), Crohn’s disease (CD), or indeterminate colitis (IBDU/IC) were invited to answer an anonymous survey, which included a 5-point Likert scale to evaluate adherence to therapies. Independent variables associated with inadequate adherence were evaluated. Results. Overall, 447 UC/IBDU and 135 CD patients were enrolled. Median age was 37 years (range 21-72); 39.8% were male; median time from diagnosis was 6 years (0.5-35). 91.4% were under treatment with at least one oral medication; 50.3% of patients reported inadequate adherence to oral medications. Patients with UC/IBDU had a lower risk of inadequate adherence when compared to patients with CD (OR 0.57 (0.37-0.87)). 21.8% reported inadequate adherence to biologics; subcutaneous administration was significantly associated with inadequate adherence to biologics (OR 4.8 (1.57-14.66)). Conclusion. Inadequate treatment adherence is common among patients with IBD, and potentially modifiable factors were identified.

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Adherence and quality of care in IBD

Abstract: Predictors for non-adherence were young age and smoking. High adherence rates could be explained by a high patient satisfaction and a high degree of shared decision making.

Cited by 29 publications

References 27 publications

Patients’ perception of their involvement in shared treatment decision making: Key factors in the treatment of inflammatory bowel disease

Patients’ perception of their involvement in shared treatment decision making: Key factors in the treatment of inflammatory bowel disease

Patient Preference and Physician Perceptions of Patient Preference for Oral Pharmaceutical Formulations: Results from a Real-Life Survey

Treatment Adherence in Inflammatory Bowel Disease Patients from Argentina: A Multicenter Study

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