Adéquation des apports en nutrition parentérale : poches à la carte ou prémélanges industriels ?

Foulmann, Katy; Charpiat, B.; Gadot, A.; Gerard-Boncompain, M.

doi:10.1016/j.nupar.2004.04.003

Cited by 5 publications

(4 citation statements)

References 6 publications

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“…In another recent study by Nagelkerke et al, 32% of pediatric patients on home PN received commercial standard solutions (7). In this study, patients on home PN with standard formulations for more than six months had similar growth after 24 months and no increase in biochemical and electrolyte disturbances when compared to individualized PN (7); however, additional studies evaluating the nutritional, growth and development outcomes of long‐term use of standard PN solutions are needed (10,19).…”

Section: Discussionmentioning

confidence: 90%

“…For that purpose, we performed a quantitative analysis using three successive criteria (NPC:volume ratio, NPC:N ratio and electrolyte concentration), as previously described by Quessada et al (16). In a study by Foulmann et al, these same criteria were also defined as fundamental when choosing an adequate standard PN formulation in an adult population (19). In fact, a similar sequential approach is used when prescribing individualized PN at our unit.…”

Section: Discussionmentioning

confidence: 99%

“…The prescription of standard PN solutions will always demand a compromise between the patient's requirements and the composition of available solutions. The clinical and metabolic consequences of allowing even for small variations in prescription in the long term are currently not known (19). Of note, there is a lack of commercial PN formulations designed to meet the specific quantitative and qualitative metabolic needs of pediatric patients.…”

Section: Discussionmentioning

confidence: 99%

“…Patients were started on home PN at a median age of 18 months (2 months-16 years). By the end of the study period, 17 (71%) patients remained on home PN (median duration of 16 months; 1 month-12 years) with a median of 6.5 infusions per week (2-7) and 11 hours per day (9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24). Of the remaining seven, one patient (4%) died during the study period due to complications from Mowat-Wilson syndrome while on palliative care, and one (4%) was transferred to another hospital less than 1 month after starting home PN.…”

Section: Patient Characteristicsmentioning

confidence: 99%

See 3 more Smart Citations

Could Commercial Formulations Replace Individualized Prescription in Pediatric Home Parenteral Nutrition?

Ferreira

Guerra

Ferreras

et al. 2021

Journal of Pediatric Gastroenterology &Amp; Nutrition

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Objectives:Standard parenteral nutrition (PN) solutions are safe and can meet the nutritional requirements of a significant number of pediatric patients. However, they may not always be adequate for those on long term PN. We aimed to compare the composition of individually tailored prescriptions in a pediatric population on home PN with that of available commercial PN formulations.Methods:Retrospective analysis of the individual prescriptions of metabolically stable pediatric patients on home PN over a 1-year period (March 2019 to March 2020). These were compared with commercially available solutions with electrolytes, and replacement was considered adequate if three successive criteria were met: non-protein calorie to volume ratio (maximum variation 15%); non-protein calorie to nitrogen ratio (NPC:N) (maximum variation either 20% for long term use or 35% for possible short term use); electrolyte concentration (maximum increase 20%).Results:Twenty-four patients were included (67% male; median age 7.5 years). The most common diagnosis was short bowel syndrome (58%). Replacement with a standard formulation was considered appropriate for possible short term use (maximum variation of 35% in NPC:N) in 16 (67%) patients and for long term use (maximum variation of 20% in NPC:N), the number of patients decreased to 10 (42%).Conclusions:Standard PN solutions can be adequate for a significant proportion of pediatric patients on home PN. Their use in the short term may also be appropriate in holiday periods or in settings of limited resources or restricted access to hospital facilities, such as those imposed by the COVID-19 pandemic.

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Section: Discussionmentioning

confidence: 90%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%