“…The distribution of AC isoforms in the digestive system was also reviewed (Sabbatini et al, 2014). Similar to the other organs/cells reported, mRNA for multiple ACs were found in hepatocytes and cholangiocytes (Strazzabosco et al, 2009), as well as in the pancreatic acini and duct (Sabbatini et al, 2013). Another paper describing the cAMP signaling elements in lung reported the AC protein/mRNA expression patterns in several tissues and cells including bronchial epithelium, vascular endothelium, airway smooth muscle cells, vascular smooth muscle cells, pulmonary fibroblasts (WI-38 cells), and inflammatory cells (Oldenburger et al, 2012).…”