Adenomyomatosis of the Gallbladder: The “Good Omen” Comet

Mariani, Peter J.; Hsue, Andrea

doi:10.1016/j.jemermed.2009.08.029

Cited by 12 publications

(5 citation statements)

References 18 publications

(32 reference statements)

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“…Such ring-down has been proposed to result from reverberation between the near and far surfaces of the sinuses themselves, closely adjacent intrasinus papillary projections, or contained cholesterol crystals. Sonographic findings of ring-down and polypoid projections of <10 mm suggest ADMG [3–5]. …”

Section: Discussionmentioning

confidence: 99%

Description of the First Case of Adenomyomatosis of the Gallbladder in an Infant

Zárate

Bosanko

Jarasvaraparn

et al. 2014

Case Reports in Pediatrics

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We report here the case of the youngest patient with adenomyomatosis of the gallbladder in a female infant diagnosed at 4 months of age. This diagnosis was made based on characteristic ultrasonography findings in a patient that was undergoing routine surveillance for a suspected clinical diagnosis of Beckwith-Wiedemann syndrome. The patient remains asymptomatic and currently no surgical interventions have been needed. We review the pathophysiology and ultrasonographic findings of this rare condition and present a comparison with the only other four pediatric cases of adenomyomatosis of the gallbladder.

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Section: Discussionmentioning

confidence: 99%

Description of the First Case of Adenomyomatosis of the Gallbladder in an Infant

Zárate

Bosanko

Jarasvaraparn

et al. 2014

Case Reports in Pediatrics

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“…Various methods are used to differentiate GBC from BGML before surgery. Ultrasonography is a common tool used for the discovery of gallbladder lesions with low accuracy, which depends largely on the operator's skills (20,21). For example, among polypoid lesions, the gallbladder sludge ball may mimic true gallbladder polyps, appearing as immobile mass lesion (22).…”

Section: Introductionmentioning

confidence: 99%

Development and Validation of a Nomogram for Early Detection of Malignant Gallbladder Lesions

Chen

Cao

Bai

et al. 2019

Clinical and Translational Gastroenterology

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OBJECTIVES:Preoperative decision-making for differentiating malignant from benign lesions in the gallbladder remains challenging. We aimed to create a diagnostic nomogram to identify gallbladder cancer (GBC), especially for incidental GBC (IGBC), before surgical resection.METHODS:A total of 587 consecutive patients with pathologically confirmed gallbladder lesions from a hospital were randomly assigned to a training cohort (70%) and an internal validation cohort (30%), with 287 patients from other centers as an external validation cohort. Radiological features were developed by the least absolute shrinkage and selection operator logistic regression model. Significant radiological features and independent clinical factors, identified by multivariate analyses, were used to construct a nomogram.RESULTS:A diagnostic nomogram was established by age, CA19.9, and 6 radiological features. The values of area under the curve in the internal and external validation cohorts were up to 0.91 and 0.89, respectively. The calibration curves for probability of GBC showed optimal agreement between nomogram prediction and actual observation. Compared with previous methods, it demonstrated superior sensitivity (91.5%) and accuracy (85.1%) in the diagnosis of GBC. The accuracy using the nomogram was significantly higher in GBC groups compared with that by radiologists in the training cohort (P < 0.001) and similarly in each cohort. Notably, most of the IGBC, which were misdiagnosed as benign lesions, were successfully identified using this nomogram.DISCUSSION:A novel nomogram provides a powerful tool for detecting the presence of cancer in gallbladder masses, with an increase in accuracy and sensitivity. It demonstrates an unprecedented potential for IGBC identification.

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“…The intramural foci may show "comet tail" reverberation artifacts, indicative of cholesterol crystals within Rokitansky-Aschoff sinuses. These "comet tails" extend from the near wall into the anechoic lumen (Boscak et al 2006;Mariani and Hsue 2011). Postcontrast CT images demonstrate the characteristic rosary sign or necklace sign, formed by the enhanced epithelial structures in the intramural diverticula surrounded by the non-enhancing hypertrophied muscle tissue (Chao et al 1992;Zissin et al 2003;Ching et al 2007;Poonam et al 2008;Stunell et al 2008).…”

Section: Clinical and Imaging Featuresmentioning

confidence: 99%

Hyperplastic Lesions and Metaplastic Changes of the Gallbladder

Zimmermann¹

2016

Tumors and Tumor-Like Lesions of the Hepatobiliary Tract

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Adenomyomatosis of the Gallbladder: The “Good Omen” Comet

Cited by 12 publications

References 18 publications

Description of the First Case of Adenomyomatosis of the Gallbladder in an Infant

Description of the First Case of Adenomyomatosis of the Gallbladder in an Infant

Development and Validation of a Nomogram for Early Detection of Malignant Gallbladder Lesions

Hyperplastic Lesions and Metaplastic Changes of the Gallbladder

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